STAT5A
signal transducer and activator of transcription 5A
別名:
MGF, STAT5
Species:
Human STAT5A (6776), Mouse Stat5a (20850), Rat Stat5a (24918), dog STAT5A (490968), Horse STAT5A (100052904), domestic cat STAT5A (101090913), cow STAT5A (282375), sheep STAT5A (443419), naked mole-rat Stat5a (101723770), domestic guinea pig Stat5a (100716811)
UniProtKB ID:
遺伝子ID:
- Human(6776) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
- Mouse(20850) signal transducer and activator of transcription 5A
- Rat(24918) signal transducer and activator of transcription 5A
- dog(490968) signal transducer and activator of transcription 5A
- Horse(100052904) signal transducer and activator of transcription 5A
- domestic cat(101090913) signal transducer and activator of transcription 5A
- cow(282375) signal transducer and activator of transcription 5A
- sheep(443419) signal transducer and activator of transcription 5A
- naked mole-rat(101723770) signal transducer and activator of transcription 5A
- domestic guinea pig(100716811) signal transducer and activator of transcription 5A
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 8-5-2, clone 8-5-2, Upstate®, from mouse,
交差性
bovine, human, mouse, rat, sheep
アプリケーション
western blot
抗STAT5A抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal, culture supernatant, clone A11W, from rabbit,
交差性
bovine, chimpanzee, human, mouse, rat
アプリケーション
western blot
抗STAT5A抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody, serum, Upstate®,
交差性
human, mouse, rat
アプリケーション
western blot
Proteins
製品番号
詳細
Species
STAT5、Hisタグ融合 ヒト, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human