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Merck

PRKCH

protein kinase C, eta

別名:
PKC-L, PKCL, PRKCL, nPKC-eta
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5583) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq, Jul 2008]
  • Mouse(18755) protein kinase C, eta
  • Rat(81749) protein kinase C, eta
  • cow(518542) protein kinase C, eta
  • sheep(101105574) protein kinase C, eta
  • naked mole-rat(101716769) protein kinase C, eta
  • Domestic Rabbit(100344184) protein kinase C, eta
  • domestic guinea pig(100736222) protein kinase C, eta
  • chicken(423518) protein kinase C, eta
  • Horse(100051560) protein kinase C, eta
  • domestic cat(101082413) protein kinase C, eta
  • dog(490722) protein kinase C, eta

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Small Molecule - Agonist

製品番号
詳細
Species
オレイン酸, ≥99% (GC),
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-phospho-PKCη (Thr655) Antibody, Upstate®, from rabbit,
交差性
human
アプリケーション
western blot
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-PRKCH antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
キサントン, 97%,
Species
mouse
H-7 二塩酸塩, ≥98% (HPLC),
Species
human
タモキシフェン クエン酸塩, ≥99%,
Species
human
オレイン酸, ≥99% (GC),
Species
human
UCN-01, ≥97% (HPLC), powder,
Species
human

Proteins

製品番号
詳細
Species
PKC η Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKC eta. For use in Kinase Assays.,
Species
human
PKCη、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Prkch,
Species
mouse
MISSION® esiRNA, targeting human PRKCH,
Species
human