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Merck

LCK

lymphocyte-specific protein tyrosine kinase

別名:
LSK, YT16, p56lck, pp58lck
Species:
Human LCK (3932), Mouse Lck (16818), Rat Lck (313050), sheep LCK (100216439), Domestic Rabbit LCK (100349102), domestic guinea pig Lck (100728811), naked mole-rat Lck (101714396), Zebrafish lck (414333), cow LCK (508890), Horse LCK (100146139) ...詳細
UniProtKB ID:
P06239, D3DPP8, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q7RTZ3
遺伝子ID:
  • Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
  • Mouse(16818) lymphocyte protein tyrosine kinase
  • Rat(313050) lymphocyte-specific protein tyrosine kinase
  • sheep(100216439) lymphocyte-specific protein tyrosine kinase
  • Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
  • domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase
  • naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
  • Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
  • cow(508890) lymphocyte-specific protein tyrosine kinase
  • Horse(100146139) lymphocyte-specific protein tyrosine kinase
  • domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
  • dog(478151) lymphocyte-specific protein tyrosine kinase
  • chicken(396460) lymphocyte-specific protein tyrosine kinase

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ELISA

製品番号
詳細
Species
RAB0974
Phosphotyrosine LCK / Tyrosine-protein Kinase Lck ELISA Kit, ,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
536954
ロスマリン酸, 96%,
Species
human
594687
α-セキシチオフェン, ,
Species
human, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
06-583
抗Lck抗体, Upstate®, from rabbit,
交差性
human
アプリケーション
immunoprecipitation (IP)
western blot
SAB4300118
Anti-phospho-LCK (pTyr394) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot
HPA003494
Anti-LCK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
western blot
SAB4504459
Anti-phospho-Lck (pTyr393) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
western blot
SAB5701751
Anti-Phospho-LCK-Y394 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
249548
2-ナフタレンスルホン酸, technical grade, 70%,
Species
human
186341
1-ナフタレンスルホン酸, >50%,
Species
human
N5602
1-ナフチル ホスファート, 99%,
Species
human
C8863
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Species
human
CDS023580
ラゾパニブ, ,
Species
human

Proteins

製品番号
詳細
Species
L2792
GSTタグ付加活性型LCK ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
EMU068551
MISSION® esiRNA, targeting mouse Lck,
Species
mouse
EHU064811
MISSION® esiRNA, targeting human LCK,
Species
human