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Merck

GRIN2B

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

別名:
GluN2B, MRD6, NMDAR2B, NR2B, hNR3
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2904) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008]
  • Mouse(14812) glutamate receptor, ionotropic, NMDA2B (epsilon 2)
  • Rat(24410) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • chicken(417965) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • dog(494009) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic cat(101094356) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • Horse(100063746) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • cow(537804) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic guinea pig(100731840) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • naked mole-rat(101723091) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • sheep(101118179) glutamate receptor, ionotropic, N-methyl D-aspartate 2B

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Small Molecule - Agonist

製品番号
詳細
Species
Reversin 205, ≥98% (HPLC), film,
Species
mouse, rat, human
D-シクロセリン, synthetic,
Species
human
N-メチル-D-アスパラギン酸, ≥98% (TLC), solid,
Species
human, rat
(S)-AMPA, ≥97%,
Species
mouse, human, rat
L-グルタミン酸, ReagentPlus®, ≥99% (HPLC),
Species
rat, human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
アカンプロサートカルシウム, ≥98% (HPLC), powder,
Species
human
アカンプロサートカルシウム, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
アカンプロサートカルシウム, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
DL-2-アミノアジピン酸, ≥99%,
Species
rat
2-フェニルキノリン, 99%,
Species
rat
Ro 25-6981 塩酸塩 水和物, ≥98% (HPLC), powder,
Species
human
Ro 8-4304, solid,
Species
human
スペルミン, ≥97%,
Species
rat, human

Antibodies

製品番号
詳細
交差性
アプリケーション
PhosphoDetect Anti-NMDA NR2B (pTyr¹⁴⁷²) Rabbit pAb, liquid, Calbiochem®,
交差性
rat
アプリケーション
Anti-GRIN2B antibody produced in rabbit, affinity isolated antibody,
交差性
horse, human, mouse, rabbit, rat
アプリケーション
immunohistochemistry
western blot
Anti-NMDAR2B Antibody, clone 5C18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
bovine, canine, feline, monkey, mouse, rat
アプリケーション
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-GRIN2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-NMDAR2B antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot

Small Molecule - Blocker

製品番号
詳細
Species
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Species
human
アグマチン 硫酸塩, ≥97%, powder,
Species
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
ペンタミジン イセチオン酸塩, powder,
Species
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
L-グルタミン酸, ReagentPlus®, ≥99% (HPLC),
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GRIN2B,
Species
human
MISSION® esiRNA, targeting mouse Grin2b,
Species
mouse