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Merck

GRIA4

glutamate receptor, ionotropic, AMPA 4

別名:
GLUR4, GLUR4C, GLURD, GluA4
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2893) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
  • Mouse(14802) glutamate receptor, ionotropic, AMPA4 (alpha 4)
  • Rat(29629) glutamate receptor, ionotropic, AMPA 4
  • chicken(396137) glutamate receptor, ionotropic, AMPA 4
  • dog(489427) glutamate receptor, ionotropic, AMPA 4
  • Horse(100061561) glutamate receptor, ionotropic, AMPA 4
  • cow(529904) glutamate receptor, ionotrophic, AMPA 4
  • domestic cat(101087003) glutamate receptor, ionotropic, AMPA 4
  • domestic guinea pig(100728256) glutamate receptor, ionotropic, AMPA 4
  • naked mole-rat(101698538) glutamate receptor, ionotropic, AMPA 4
  • sheep(443274) glutamate receptor, ionotropic, AMPA 4

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Small Molecule - Agonist

製品番号
詳細
Species
2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド, ≥98% (HPLC), solid,
Species
human
シクロチアジド, ,
Species
human, rat
(±)-AMPA, solid,
Species
rat
(S)-AMPA, ≥97%,
Species
mouse, human, rat
カイニン酸 一水和物, ≥99% (TLC),
Species
human, mouse, rat

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
CX546, ≥98% (HPLC), solid,
Species
human
ピラセタム, ,
Species
human, rat
シクロチアジド, ,
Species
human, rat
カイニン酸 一水和物, ≥99% (TLC),
Species
human, mouse, rat
トピラマート, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
GYKI 52466 塩酸塩, solid,
Species
human
ピラセタム, ,
Species
human, rat
CNQX 二ナトリウム塩 水和物, ≥98% (HPLC), solid,
Species
human
NBQX 二ナトリウム塩 水和物, ≥98% (HPLC),
Species
human
(±)-AMPA, solid,
Species
rat

Antibodies

製品番号
詳細
交差性
アプリケーション
抗グルタミン酸受容体4抗体, Chemicon®, from rabbit,
交差性
mouse, rat
アプリケーション
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Gria4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
Anti-GluR4/GluA4/GRIA4 Antibody, clone 4M5D0, Rabbit Monoclonal, ,
交差性
mouse, rat
アプリケーション
western blot
Anti-GLUR4 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
抗GRIA4抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

製品番号
詳細
Species
シクロチアジド, ,
Species
human, rat
キヌレン酸, ≥98%,
Species
rat, human
トピラマート, United States Pharmacopeia (USP) Reference Standard,
Species
human
トピラマート 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
トピラマート, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
シクロチアジド, ,
Species
human, rat
(±)-AMPA, solid,
Species
rat
カイニン酸 一水和物, ≥99% (TLC),
Species
human, mouse, rat
L-グルタミン酸, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-グルタミン酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GRIA4,
Species
human
MISSION® esiRNA, targeting mouse Gria4,
Species
mouse