コンテンツへスキップ
Merck

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

別名:
DNMT3A2, M.HsaIIIA
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
Anti-DNMT3A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, human, mouse, rat
アプリケーション
ELISA
western blot
Anti-DNMT3A2 Antibody, from rabbit,
交差性
human
アプリケーション
ELISA
immunocytochemistry

western blot
Anti- DNMT3A antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-DNMT3A antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
5-アザ-2′-デオキシシチジン, ≥97%,
Species
human
5-アザシチジン, United States Pharmacopeia (USP) Reference Standard,
Species
human
5-アザシチジン, Hybri-Max, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Species
human
5-アザシチジン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
5-アザシチジン, ≥98% (HPLC),
Species
human

Proteins

製品番号
詳細
Species
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
Species
human
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human DNMT3A,
Species
human
MISSION® esiRNA, targeting mouse Dnmt3a,
Species
mouse