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Merck

CYP51A1

cytochrome P450, family 51, subfamily A, polypeptide 1

別名:
CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
Species:
Human CYP51A1 (1595), chicken CYP51A1 (420548), cow CYP51A1 (505060), dog CYP51A1 (475225)
UniProtKB ID:
Q16850, A4D1F8, B2RAI4, B4DJ55, O00770, O00772, Q16784, Q8N1A8
遺伝子ID:
  • Human(1595) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • chicken(420548) cytochrome P450, family 51, subfamily A, polypeptide 1
  • cow(505060) cytochrome P450, family 51, subfamily A, polypeptide 1
  • dog(475225) cytochrome P450, family 51, subfamily A, polypeptide 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
HPA043508
Anti-CYP51A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
MABS1259
Anti-CYP51A1 Antibody, clone N6-P2H5*G8, clone N6-P2H5*G8, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
HPA041325
Anti-CYP51A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
western blot
SAB2107501
Anti-CYP51A1 antibody produced in rabbit, affinity isolated antibody,
交差性
dog, guinea pig, horse, human, rat
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
K1003
ケトコナゾール, 99.0-101.0% (EP, titration),
Species
mouse, human, rat

esiRNA

製品番号
詳細
Species
EHU105301
MISSION® esiRNA, targeting human CYP51A1, LRRD1,
Species
human