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Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

別名:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Phospho-IKKα/β-S176/180 antibody produced in rabbit, ,
交差性
human
アプリケーション
western blot
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
交差性
mouse
アプリケーション
western blot
Anti-CHUK (Ab-23) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-phospho-IKK-α/β (pSer180/181) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
bovine, canine, feline, human, monkey, mouse, porcine, rat
アプリケーション
affinity binding assay
immunohistochemistry

inhibition assay

western blot

Proteins

製品番号
詳細
Species
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Species
human
IKK α 、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Chuk,
Species
mouse
MISSION® esiRNA, targeting human CHUK,
Species
human

Small Molecule - Substrate

製品番号
詳細
Species
IKK Substrate Peptide, ,
Species
human