BACE1
beta-site APP-cleaving enzyme 1
別名:
ASP2, BACE, HSPC104
Species:
Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Zebrafish bace1 (403005), cow BACE1 (614333), Horse BACE1 (100071137), domestic cat BACE1 (101086840), dog BACE1 (489390), chicken BACE1 (419768), sheep BACE1 (101119667) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- Mouse(23821) beta-site APP cleaving enzyme 1
- Rat(29392) beta-site APP cleaving enzyme 1
- Zebrafish(403005) beta-site APP-cleaving enzyme 1
- cow(614333) beta-site APP-cleaving enzyme 1
- Horse(100071137) beta-site APP-cleaving enzyme 1
- domestic cat(101086840) beta-site APP-cleaving enzyme 1
- dog(489390) beta-site APP-cleaving enzyme 1
- chicken(419768) beta-site APP-cleaving enzyme 1
- sheep(101119667) beta-site APP-cleaving enzyme 1
- Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
- naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
- domestic guinea pig(100135485) beta-site APP cleaving enzyme 1
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ELISA
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Activity Assay
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Antibodies
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交差性
アプリケーション
抗BACE 1, N-末端 (46-62) ウサギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-BACE Antibody, CT, clone 61-3E7, clone 61-3E7, Chemicon®, from mouse,
交差性
human, mouse, primate, rat
アプリケーション
immunoprecipitation (IP)
western blot
western blot
抗BACE 1, C末端(485-501)抗体 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
microarray
western blot
western blot
抗BACE1抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-BACE Antibody, CT, Chemicon®, from rabbit,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Kits
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Proteins
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Species
β-セクレターゼ ヒト, recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000 units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution,
Species
human