D4540

Dimethyl sulfoxide

≥99.5% (GC), suitable for plant cell culture

• Synonym(s): DMSO
• Linear Formula: (CH₃)₂SO
• CAS Number: 67-68-5
• Molecular Weight: 78.13
• Beilstein: 506008
• EC Number: 200-664-3
• MDL number: MFCD00002089
• PubChem Substance ID: 24893881
• NACRES: NA.71

Properties

• vapor density: 2.7 (vs air)
• Quality Level: 200
• vapor pressure: 0.42 mmHg ( 20 °C)
• Assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 573 °F
• expl. lim.: 42 %, 63 °F
• technique(s): cell culture | plant: suitable; cryopreservation: suitable
• impurities: <0.1% water (Karl Fischer)
• color: colorless
• refractive index: n20/D 1.479 (lit.)
• bp: 189 °C (lit.)
• mp: 16-19 °C (lit.)
• solubility: H₂O: miscible (completely)
• density: 1.10 g/mL (lit.)
• SMILES string: CS(C)=O
• InChI: 1S/C2H6OS/c1-4(2)3/h1-2H3
• InChI key: IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Description

Application

Dimethyl sulfoxide has been used:

• in the preparation of bisphenol A (BPA)
• in cell proliferation assay (MTT assay)
• in chemosensitivity assay
• as the vehicle control in all experiments like apoptosis assay
• in ethoxyresorufin-O-deethylation (EROD) assay

Biochem/physiol Actions

DMSO (dimethyl sulfoxide), an organic solvent possesses several pharmaceutical activities such as analgesic, diuretic, bacteriostatic, membrane-penetrant, anti-inflammatory, vasodilatory and cholinesterase inhibitory effects. It is a by-product of the lumber industry and used as an industrial solvent. DMSO also serves as a therapeutic agent to treat interstitial cystitis and arthritis.

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 188.6 °F - closed cup
• Flash Point(C): 87 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves