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Safety Information

76735

Supelco

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride

for GC derivatization, LiChropur™, ≥99.0% (AT)

Synonym(s):

PFBHA·HCl

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About This Item

Linear Formula:
C6F5CH2ONH2·HCl
CAS Number:
57981-02-9
Molecular Weight:
249.57
Beilstein:
4031190
EC Number:
261-057-7
MDL number:
MFCD00012953
UNSPSC Code:
12000000
PubChem Substance ID:
329767306
NACRES:
NA.22

grade

for GC derivatization

Quality Level

100

Assay

≥99.0% (AT)

form

solid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Alkylations

technique(s)

gas chromatography (GC): suitable

mp

212-218 °C
227 °C (subl.) (lit.)

solubility

H2O: 5%, clear

SMILES string

Cl.NOCc1c(F)c(F)c(F)c(F)c1F

InChI

1S/C7H4F5NO.ClH/c8-3-2(1-14-13)4(9)6(11)7(12)5(3)10;/h1,13H2;1H

InChI key

HVMVKNXIMUCYJA-UHFFFAOYSA-N

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General description

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA.HCl) is a derivatizing agent.

Application

PFBHA.HCl has been used for derivatization of metabolites with carbonyl groups followed by analysis via GC-MS. It has also been used in aldehyde derivatization followed by aldehydic hydrolysis using GC/MS.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Sensitive derivatizing agent for electron capture gas chromatographic analysis of carbonyl-containing compounds: keto steroids and carbohydrates

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

76735-BULK:
76735-VAR:
76735-10X1G:
76735-250MG:
76735-1G-KC:
76735-1G:
76735-INTR:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG5577
BCCF8143
BCCD9493
BCCD2221
BCCB4662

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Stadelmann-Ingrand S
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Degradation of fluoranthene by Pasteurella sp. IFA and Mycobacterium sp. PYR-1:isolation and identification of metabolites.
Sepic E, Bricelj M, Leskovsek H.
Journal of Applied Microbiology, 85(4), 746-754 null
Birgit Schulze et al.
Analytical biochemistry, 348(2), 269-283 (2005-11-26)
A GC-MS-based method for the simultaneous quantification of common oxylipins along with labile and highly reactive compounds based on in situ derivatization with pentafluorobenzyl hydroxylamine to the corresponding O-2,3,4,5,6-pentafluorobenzyl oximes (PFB oximes) is presented. The approach covers oxo derivatives such
Chunhui Deng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 810(2), 269-275 (2004-09-24)
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