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15238

Supelco

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane

for GC derivatization, LiChropur, contains 1% TMCS, 99% (excluding TMCS)

Synonym(s):
Silylating mixture V, BSTFA + TMCS
Linear Formula:
CF3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
Molecular Weight:
257.40
Beilstein:
2050024
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

grade

for GC derivatization

assay

≥98.5% (excluding chlorotrimethylsilane, GC)
99% (excluding TMCS)

form

liquid

quality

LiChropur
contains 1% TMCS

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.384 (lit.)

bp

45-50 °C/14 mmHg (lit.)

density

0.97 g/mL (lit.)

SMILES string

C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F

InChI

1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+

InChI key

XCOBLONWWXQEBS-KPKJPENVSA-N

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Application

Learn more in the Product Information

Packaging

5, 25, 100 mL in glass bottle
Clear borosilicate glass, high hydrolytic resistance (Type I)

Other Notes

The position of the silyl groups has not been unequivocally established. It has been referred to as both N,N and N,O.
Silylating mixture used for the silylation of various compounds

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

44.1 °F - closed cup

Flash Point(C)

6.7 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

W. Greenway et al.
Journal of Chromatography A, 519, 145-145 (1990)
W.M. Hammargren et al.
Analytica Chimica Acta, 247, 201-201 (1991)
DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine.
Helbock H
Proceedings of the National Academy of Sciences of the USA, 95 (1), 288-293 (1998)
J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
Metabolism of arachidonate through NADPH-dependent oxygenase of renal cortex.
Proceedings of the National Academy of Sciences of the USA, 78 (12), 7375-7378 (1981)

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