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672112

Sigma-Aldrich

Urokinase, Human Urine

Synonym(s):

Urokinase, Human Urine, uPA

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About This Item

CAS Number:
9039-53-6
Enzyme Commission number:
3.4.99.26 (BRENDA, IUBMB)
MDL number:
MFCD00132566
UNSPSC Code:
12352202
NACRES:
NA.25

form

lyophilized solid

Quality Level

100

specific activity

≥100,000 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

shipped in

ambient

storage temp.

−20°C

General description

Native urokinase from human urine. A thrombolytic agent that converts plasminogen to plasmin. A mixture of high molecular weight (54 kDa) and low molecular weight (33 kDa) urokinase.
Note: 1 unit = 1 CTA unit = 0.7 Ploug units. 1 KU = 1000 units.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of enzyme equal to an international standard tested by the fibrinolytic method of Johnson, et al.

Physical form

Lyophilized from 200 mM mannitol, 100 mM NaCl, 50 mM Tris-HCl, 0.1% PEG, pH 7.5.

Preparation Note

Prepared from urine of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
Reconstitute in distilled H₂O

Other Notes

Bell, W.R. 1975. Semin. Thromb. Res.2, 1.
Johnson, A.J., et al. 1969. Thromb. Diath. Haemorrh. 21, 259.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

672112-10KU:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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