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527621

Sigma-Aldrich

Plasmin, Human Plasma

Synonym(s):

Plasmin, Human Plasma

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About This Item

CAS Number:
9001-90-5
Enzyme Commission number:
3.4.21.7 (BRENDA, IUBMB)
MDL number:
MFCD00131921
UNSPSC Code:
12352202
NACRES:
NA.25

form

liquid

Quality Level

100

specific activity

≥5 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−20°C

General description

Native plasmin from human plasma. Catalyzes the hydrolysis of peptides, arginine and lysine esters and converts fibrin into soluble products.
Native plasmin from human plasma. Catalyzes the hydrolysis of peptides, arginine and lysine esters, and converts fibrin into soluble products.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol of N-tosyl-Gly-Pro-Lys-pNA per min at 25°C, pH 7.8.

Physical form

In 100 mM sodium phosphate, 1 mM 6-aminohexanoic acid, 25% glycerol, pH 7.3.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Federici, A.B., et al. 1993. Blood 81, 720.
Hoffmann, J.J., and Janssen, W.C. 1992. Thromb. Res. 67, 711.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

527621-U:
527621-10U:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J J Hoffmann et al.
Thrombosis research, 67(6), 711-719 (1992-09-15)
The mechanisms by which thrombolytic agents affect platelet function are not yet elucidated. The aim of the present study was to investigate the effects of plasmin, generated by thrombolytic agents in plasma, on platelet glycoproteins (GP) Ib and IIb/IIIa. Platelet-rich
A B Federici et al.
Blood, 81(3), 720-725 (1993-02-01)
The behavior of plasma von Willebrand factor (vWF) in patients with acute leukemia (n = 5), decompensated cirrhosis (n = 10), and acute pancreatitis (n = 5) was investigated to evaluate whether the systemic proteolytic states associated with these diseases

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