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914916

Sigma-Aldrich

Biotin-SS-tyramide

≥95%

Synonym(s):

N-(2-((3-(4-Hydroxyphenethylamino)-3-oxopropyl)disulfanyl)ethyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, Cleavable biotin-phenol, Cleavable biotin-tyramide linker

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About This Item

Empirical Formula (Hill Notation):
C23H34N4O4S3
Molecular Weight:
526.74
UNSPSC Code:
12352200
NACRES:
NA.22

Quality Level

100

Assay

≥95%

form

powder

storage temp.

−20°C

Application

Biotin-SS-tyramide is a cleavable, biotinylated reagent for tyramide signal amplification used in many applications including immunohistochemistry, in situ hybridization, electron microscopy, ELISA, and others. It can be used together with both chromogenic and fluorescence visualization methods. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions or by glutathione in the lysosome.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Other Notes

Biotinylation and isolation of an RNA G-quadruplex based on its peroxidase-mimicking activity

New Insights into the DT40 B Cell Receptor Cluster Using a Proteomic Proximity Labeling Assay

A Catalysis-Based Selection for Peroxidase Antibodies with Increased Activity

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

914916-VAR:
914916-BULK:
914916-100MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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