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704083

Sigma-Aldrich

Trifluoromethanesulfonic anhydride solution

1 M in methylene chloride

Synonym(s):

Perfluoromethanesulfonic anhydride solution, Triflic anhydride solution

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About This Item

Empirical Formula (Hill Notation):
C2F6O5S2
CAS Number:
358-23-6
Molecular Weight:
282.14
MDL number:
MFCD00000408
UNSPSC Code:
12352101
PubChem Substance ID:
329762092
NACRES:
NA.22

form

liquid

Quality Level

100

concentration

1 M in methylene chloride

refractive index

n20/D 1.402

density

1.359 g/mL at 25 °C

functional group

fluoro
triflate

storage temp.

2-8°C

SMILES string

FC(F)(F)C(=O)OC(=O)C(F)(F)F

InChI

1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8

InChI key

WJKHJLXJJJATHN-UHFFFAOYSA-N

Application

Catalyst for synthesis of Bacteroides fragilis zwitterionic polysaccharide Ai tetrasaccharide repeating unit via glycosylation

Reagent for stereoselective synthesis of mennosazide methyl uronate donors

Activator for direct glycosylation with anomeric hydroxy sugars
Trifluoromethanesulfonic anhydride solution is generally used to convert hydroxyl groups to triflic esters. It can be used to prepare triflic azide for azido amino acid synthesis.

Signal Word

Danger

Hazard Statements

H272,H314,H335,H336,H351

Hazard Classifications

Carc. 2 - Eye Dam. 1 - Ox. Liq. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

704083-100ML:4548173299631
704083-BULK:
704083-VAR:
704083-25ML:4548173299648

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Certificates of Analysis (COA)

Lot/Batch Number
MKCN6454
MKCM7293
MKCL6271
MKCK3118
MKCJ7498

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The [(18)F]fluoroethyl moiety has been widely utilized in the synthesis of (18)F-labelled compounds. The aim of this work was the reliable synthesis of [(18)F]FEtOTf with a novel strategy to increase the reactivity of the commonly used [(18)F]FEB and [(18)F]FEtOTos. [(18)F]FEtOTf
Tatsuya Higashi et al.
Journal of pharmaceutical and biomedical analysis, 117, 155-162 (2015-09-12)
The analysis of changes in the brain neurosteroid (NS) levels due to various stimuli can contribute to the elucidation of their physiological roles, and the discovery and development of new antipsychotic agents targeting neurosteroidogenesis. We developed methods for the differential
Surendra Vutti et al.
Chembiochem : a European journal of chemical biology, 16(5), 782-791 (2015-03-05)
Stable primary functionalization of metal surfaces plays a significant role in reliable secondary attachment of complex functional molecules used for the interfacing of metal objects and nanomaterials with biological systems. In principle, this can be achieved through chemical reactions either

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