1597005

Quinine sulfate

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: Quinine hemisulfate salt monohydrate, Quinine sulfate (2:1) (salt) dihydrate
• Formula empirica (notazione di Hill): C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
• Numero CAS: 207671-44-1
• Peso molecolare: 391.47
• Beilstein: 6113937
• Numero MDL: MFCD00150790
• Codice UNSPSC: 41116107
• ID PubChem: 329751013
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: quinine
• PM: monograph mol wt. 782.94
• Produttore/marchio commerciale: USP
• Punto di fusione: ~225 °C (dec.) (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
• InChI: 1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1; ZHNFLHYOFXQIOW-LPYZJUEESA-N

Descrizione

Descrizione generale

(C₂₀H₂₄N₂O₂)₂ . H₂SO₄ . 2H₂O

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Quinine sulfate is the sulfate salt of quinine, an alkaloid, obtained from the bark of Cinchona species.

Applicazioni

Quinine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Quinine Sulfate Capsules
• Quinine Sulfate Tablets

Azioni biochim/fisiol

Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319,H335
• Consigli di prudenza: P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable