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Key Documents

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69311

Supelco

Quinine

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Sinonimo/i:

6′-Methoxycinchonidine

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About This Item

Formula empirica (notazione di Hill):
C20H24N2O2
Numero CAS:
130-95-0
Peso molecolare:
324.42
Beilstein:
91867
Numero CE:
205-003-2
Numero MDL:
MFCD00198096
Codice UNSPSC:
41116107
ID PubChem:
329761562
NACRES:
NA.24

Grado

certified reference material
TraceCERT®

Livello qualitativo

300

Nome Commerciale

TraceCERT®

Durata

limited shelf life, expiry date on the label

Produttore/marchio commerciale

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Condizioni di stoccaggio

under inert gas

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

173-175 °C (lit.)

applicazioni

food and beverages

Formato

neat

Stringa SMILE

COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1
LOUPRKONTZGTKE-WZBLMQSHSA-N

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Descrizione generale

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Potassium channel blocker

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Avvertenza

Store under argon.

Note legali

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H317

Classi di pericolo

Acute Tox. 4 Oral - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

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Certificati d'analisi (COA)

Lot/Batch Number
BCCF7920
BCBV4559
BCBM5794V
BCBG6955V
BCBG6955

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(-)-Dihydroquinine phyproof® Reference Substance

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(-)-Dihydroquinine

Quinidine anhydrous

Sigma-Aldrich

Q3625

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Quinine hydrochloride dihydrate United States Pharmacopeia (USP) Reference Standard

USP

1596807

Quinine hydrochloride dihydrate

Quinine hydrochloride dihydrate BioReagent, suitable for fluorescence, ≥98.0% (NT)

Sigma-Aldrich

22630

Quinine hydrochloride dihydrate

Quinine monohydrochloride dihydrate ≥95%, FG

Sigma-Aldrich

W297607

Quinine monohydrochloride dihydrate

Quinine hydrochloride dihydrate tested according to Ph. Eur.

Sigma-Aldrich

22632

Quinine hydrochloride dihydrate

Quinidine crystallized, ≥98.0% (dried material, NT)

Sigma-Aldrich

22600

Quinidine

Xiong-Li Liu et al.
Organic letters, 15(6), 1246-1249 (2013-03-05)
A wide range of structurally diverse 3,3'-thiopyrrolidonyl spirooxindoles bearing three contiguous stereogenic centers can be smoothly obtained via a domino Michael/cyclization reaction between 3-isothiocyanato oxindoles and 3-methyl-4-nitro-5-alkenyl-isoxazoles with commercially available quinine as the catalyst under mild conditions. The protocol is
George Praygod et al.
Malaria journal, 7, 210-210 (2008-10-22)
The efficacy of intravenous quinine, which is the mainstay for treating severe malaria in children, is decreasing in South East Asia and Africa. Artemisinin derivatives are a potential alternative to quinine. However, their efficacy compared to quinine in treating severe
Jane Achan et al.
Malaria journal, 10, 144-144 (2011-05-26)
Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs. This
Hmwe Hmwe Kyu et al.
Bulletin of the World Health Organization, 87(12), 896-904 (2010-05-11)
To summarize the existing evidence on the efficacy of artemether and arteether, two artemisinin derivatives, versus quinine for treating cerebral malaria in children. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and the http://clinicaltrials.gov web site. We
Annemarie R Kreeftmeijer-Vegter et al.
Malaria journal, 12, 115-115 (2013-03-30)
Exchange transfusion (ET) has remained a controversial adjunct therapy for the treatment of severe malaria. In order to assess the relative contribution of ET to parasite clearance in severe malaria, all patients receiving ET as an adjunct treatment to parenteral
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