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Merck
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Documenti

UC448

Sigma-Aldrich

Paracetamol sulfate potassium salt

solid, ≥97% (HPLC)

Sinonimo/i:

Acetaminophen sulfate

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About This Item

Formula empirica (notazione di Hill):
C8H8KNO5S
Numero CAS:
32113-41-0
Peso molecolare:
269.32
Numero MDL:
MFCD01631667
Codice UNSPSC:
12161501
ID PubChem:
329827671
NACRES:
NA.77

Saggio

≥97% (HPLC)

Forma fisica

solid

Colore

white to off-white

Punto di fusione

163 °C

Solubilità

H2O: soluble

Temperatura di conservazione

2-8°C

Stringa SMILE

[K+].CC(=O)Nc1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C8H9NO5S.K/c1-6(10)9-7-2-4-8(5-3-7)14-15(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1
AJYPYWFCUWHZMZ-UHFFFAOYSA-M

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Descrizione generale

Paracetamol is an aminophenol derivative. It functions as an analgesic and antipyretic drug, which has weak inflammatory effect. Paracetamol is used to treat pyrexia and mild to moderate pain. It might inhibit atherosclerosis through its antioxidant activity.

Applicazioni

Paracetamol sulfate potassium salt has been used as a standard for HPLC assays of acetaminophen.

Azioni biochim/fisiol

Phase II metabolite of paracetamol.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Nota sulla preparazione

Paracetamol sulfate potassium salt is soluble in water.

Altre note

Occasionally, it may be necessary to supply as the sodium salt

Pittogrammi

CorrosionExclamation mark
GHS05,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H315,H317,H318,H335

Classi di pericolo

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

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Paracetamol: past, present, and future.
Prescott LF
American Journal of Therapeutics, 7(2), 143-147 (2000)
Karel Allegaert et al.
Acta paediatrica (Oslo, Norway : 1992), 94(9), 1273-1279 (2005-11-11)
Major changes in drug clearance and metabolism are observed during infancy, in part based on ontogenic regulation of various metabolic pathways. Since paracetamol provides a good substrate to study UGT (1A6) activity, urinary metabolites of propacetamol were determined in neonates
D Bougie et al.
Blood, 97(12), 3846-3850 (2001-06-05)
In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in
A Alberti et al.
Biological psychiatry, 46(3), 420-424 (1999-08-06)
Parents of autistic children and autism support groups often report that autistic episodes are exacerbated when the children eat certain foodstuffs such as dairy products, chocolates, wheat, corn sugar, apples, and bananas. The hypothesis that autistic behavior might be related
H Xiong et al.
The Journal of pharmacology and experimental therapeutics, 295(2), 512-518 (2000-10-25)
Previous studies have demonstrated that phenobarbital treatment impairs the biliary excretion of acetaminophen glucuronide (AG), although the transport system(s) responsible for AG excretion into bile has not been identified. Initial studies in rat canalicular liver plasma membrane vesicles indicated that
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