Passa al contenuto
Merck
Tutte le immagini(4)

Key Documents

View All Documentation

A5000

Sigma-Aldrich

Acetaminofene

meets USP testing specifications, 98.0-102.0%, powder

Sinonimo/i:

4′-idrossiacetanilide, 4-acetamidofenolo, N-(4-idrossifenil)acetammide, N-acetil-4-amminofenolo, APAP, Paracetamolo

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(4)

About This Item

Formula condensata:
CH3CONHC6H4OH
Numero CAS:
103-90-2
Peso molecolare:
151.16
Beilstein:
2208089
Numero MDL:
MFCD00002328
Codice UNSPSC:
12352111
ID PubChem:
24890930
NACRES:
NA.25

agenzia

USP/NF
meets USP testing specifications

Livello qualitativo

200

Saggio

98.0-102.0%

Forma fisica

powder

Punto di fusione

168-172 °C (lit.)

Solubilità

DMSO: 5 M
ethanol: 50 mg/mL
H2O: very slightly soluble

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
RZVAJINKPMORJF-UHFFFAOYSA-N

Informazioni sul gene

human ... FAAH(2166) , PTGS1(5742) , PTGS2(5743) , TRPV1(7442)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Applicazioni

Analgesico.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

364.3 °F - Pensky-Martens closed cup

Punto d’infiammabilità (°C)

184.6 °C - Pensky-Martens closed cup

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
MKCQ8545
MKCN0690
MKCL1130
MKCJ5427
MKCD6375

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 7

1 of 7

Aspirin meets USP testing specifications

Sigma-Aldrich

A2093

Aspirin

Ibuprofene ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofene

Propacetamol hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML1777

Propacetamol hydrochloride

Acetylsalicylic acid ≥99.0%

Sigma-Aldrich

A5376

Acetylsalicylic acid

p-Acetamidophenyl β-D-glucuronide sodium salt >98% (TLC)

Sigma-Aldrich

A4438

p-Acetamidophenyl β-D-glucuronide sodium salt

N-Acetylbenzoquinoneimine

Sigma-Aldrich

A7300

N-Acetylbenzoquinoneimine

1,4-Bis(2-methylstyryl)benzene BioReagent, suitable for scintillation, ≥98% (UV)

Sigma-Aldrich

15090

1,4-Bis(2-methylstyryl)benzene

Mohammad A Rahman et al.
Scientific reports, 9(1), 6571-6571 (2019-04-27)
Cellular CYP2E1 is well-known to mediate alcohol- (ALC) and acetaminophen- (APAP) induced toxicity in hepatic and extra-hepatic cells. Although exosomes have been gaining importance in understanding mechanism of intra- and inter-cellular communication, the functional role of drug metabolizing cytochrome P450
S M de Morais et al.
Gastroenterology, 102(2), 577-586 (1992-02-01)
Gilbert's syndrome occurs in 5%-7% of the human population and is caused by an inherited deficiency in the glucuronidation of endogenous bilirubin, resulting in its accumulation and jaundice. The authors of the present study have previously shown that rats with
Edward Munsterhjelm et al.
Anesthesiology, 103(4), 712-717 (2005-09-30)
Acetaminophen (paracetamol) is widely used for postoperative analgesia. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous system, and acetaminophen is traditionally not considered to influence platelet function. The authors studied the dose-dependent inhibition of platelet
Mitchell R McGill et al.
Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.
Garry G Graham et al.
Drug safety, 28(3), 227-240 (2005-03-01)
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.