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T5699

Sigma-Aldrich

m-3M3FBS

>97% (HPLC)

Sinonimo/i:

2,4,6-Trimethyl-N-(3-trifluoromethyl-phenyl)-benzenesulfonamide, N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide

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About This Item

Formula empirica (notazione di Hill):
C16H16F3NO2S
Numero CAS:
200933-14-8
Peso molecolare:
343.36
Numero MDL:
MFCD00095824
Codice UNSPSC:
41106300
ID PubChem:
329826829
NACRES:
NA.77

Saggio

>97% (HPLC)

Forma fisica

powder

Colore

white

Punto di fusione

114-114.8 °C (lit.)

Solubilità

DMSO: >20 mg/mL

Stringa SMILE

Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccc(c2)C(F)(F)F

InChI

1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3
ZIIUUSVHCHPIQD-UHFFFAOYSA-N

Applicazioni

m-3M3FBS has been used for MAP kinase assay in 293T cells. It has also been used for intracellular calcium analysis1. Furthermore, it has been used (at a conc. of 1 μM) as a PLC activator for sensitizing TRPA1 in HEK293t cells2.

Azioni biochim/fisiol

First known direct activator of phospholipase C (activates β2, β3, γ1, γ2, δ1 isoforms).

Nota sulla preparazione

m-3M3FBS is soluble in DMSO at a concentration that is greater than 20 mg/ml.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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