SAB5600015

Anti-Acetyl-Histone H3 (Lys56) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM179, purified immunoglobulin

• Sinonimo/i: H3K56ac, Histone H3 (acetyl K56)
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Ricombinante: expressed in HEK 293 cells
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: RM179, monoclonal; recombinant monoclonal
• Forma fisica: buffered aqueous glycerol solution
• Reattività contro le specie: human
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 0.5-1 μg/mL; immunocytochemistry: 0.5-2 μg/mL; immunohistochemistry: 1 ug/mL – 10 ug/mL; western blot: 1-2 μg/mL
• Isotipo: IgG
• N° accesso NCBI: 8350
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: acetylation (Lys56)
• Informazioni sul gene: human ... H3C1(8350)

Descrizione

Descrizione generale

Mammals contain three main classes of histone H3 variants: the replicative histones (H3.1 and H3.2), the replacement histone (H3.3) and the centromeric histone (Cenp-A). Histone H3 is located on human chromosome 6p22.

Specificità

This antibody reacts to Histone H3 acetylated at Lysine 56 (K56ac). No cross reactivity with other acetylated Lysines in histone H3.

Immunogeno

Synthetic peptide corresponding to the Acetyl-Histone H3 (Lys56)

Azioni biochim/fisiol

Histone proteins are basic building blocks of chromatin. Histone H3 K27M mutations in adult cerebellar high-grade gliomas. It controls protein-protein interactions to induce binding of trans-acting factors that drive chromatin condensation.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable