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PZ0006

Sigma-Aldrich

Exemestane

≥98% (HPLC)

Sinonimo/i:

6-Methyleneandrosta-1,4-diene-3,17-dione

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About This Item

Formula empirica (notazione di Hill):
C20H24O2
Numero CAS:
107868-30-4
Peso molecolare:
296.40
Numero MDL:
MFCD00866994
Codice UNSPSC:
51111800
ID PubChem:
329823675
NACRES:
NA.77

Saggio

≥98% (HPLC)

Forma fisica

powder

Attività ottica

[α]/D +250 to +300°, c = 1 in methanol

Colore

white to off-white

Solubilità

DMSO: ≥20 mg/mL

Temperatura di conservazione

2-8°C

Stringa SMILE

C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O

InChI

1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
BFYIZQONLCFLEV-DAELLWKTSA-N

Informazioni sul gene

human ... CYP19A1(1588)

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Azioni biochim/fisiol

Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.

Caratteristiche e vantaggi

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pittogrammi

Health hazardEnvironment
GHS08,GHS09

Avvertenze

Danger

Indicazioni di pericolo

H360,H411

Classi di pericolo

Aquatic Chronic 2 - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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