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A8980

Sigma-Aldrich

Acarbose

≥95% (HPLC)

Sinonimo/i:

4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose

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About This Item

Formula empirica (notazione di Hill):
C25H43NO18
Numero CAS:
56180-94-0
Peso molecolare:
645.60
Numero CE:
260-030-7
Numero MDL:
MFCD00869592
Codice UNSPSC:
12352201
ID PubChem:
329771024
NACRES:
NA.25

Origine biologica

bacterial (Actinoplanes)

Livello qualitativo

200

Saggio

≥95% (HPLC)

Forma fisica

powder

Impurezze

<9.4% water (Karl Fischer)

Colore

white to off-white

Solubilità

H2O (CO2 free): 50 mg/mL, clear, colorless

Temperatura di conservazione

room temp

Stringa SMILE

C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)[C@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]1N[C@H]4C=C(CO)[C@@H](O)[C@H](O)[C@H]4O

InChI

1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
XUFXOAAUWZOOIT-SXARVLRPSA-N

Informazioni sul gene

human ... AMY2A(279) , MGAM(8972)

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Applicazioni

Acarbose, a derivitized maltotriose antidiabetic drug, is a reversible α-glucosidase inhibitor used in medical studies to control the effects of Type II diabetes. Acarbose is often used as a reference to which other α-glucosidase inhibitors are compared.

Azioni biochim/fisiol

Modified tetrasaccharide that acts as a reversible α -glucosidase inhibitor.

Altre note

To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Ranee Singh et al.
Journal of feline medicine and surgery, 17(10), 848-857 (2014-10-26)
Feeding a low carbohydrate diet is recommended for diabetic cats; however, some cats may require diets containing moderate-to-high carbohydrate and may benefit from the use of therapeutic agents to improve glycemic control. The aim of the study was to determine
Muhammad Jihad Sandikapura et al.
Pakistan journal of pharmaceutical sciences, 31(2(Suppl.)), 623-635 (2018-04-08)
The study was aimed to perform aqueous extraction of two plants using different extraction methods, and evaluate their antioxidant and antidiabetic potential. Plant materials were extracted by maceration, soxhlet, sonication and fresh juice methods to produce aqueous extracts. In vitro
Alessandro Leone et al.
Nutrients, 10(10) (2018-10-17)
The hypoglycemic effect in humans of Moringa oleifera (MO) leaf powder has, to date, been poorly investigated. We assessed the chemical composition of MO leaf powder produced at Saharawi refugee camps, its in vitro ability to inhibit α-amylase activity, and
Ashley S Boath et al.
Food chemistry, 135(3), 929-936 (2012-09-08)
Polyphenol-rich extracts from certain berries inhibited α-glucosidase activity in vitro. The two most effective berry extracts, from black currant and rowanberry, inhibited α-glucosidase with IC(50) values respectively of 20 and 30μg GAE/ml and were as effective as the pharmaceutical inhibitor
Henriëtte J Rozeboom et al.
The Journal of biological chemistry, 288(37), 26764-26774 (2013-08-02)
α-1,4-Glucan lyase (EC 4.2.2.13) from the red seaweed Gracilariopsis lemaneiformis cleaves α-1,4-glucosidic linkages in glycogen, starch, and malto-oligosaccharides, yielding the keto-monosaccharide 1,5-anhydro-D-fructose. The enzyme belongs to glycoside hydrolase family 31 (GH31) but degrades starch via an elimination reaction instead of
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