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Documenti

85707

Supelco

Acido 2,5-diidrossibenzoico

matrix substance for MALDI-MS, >99.0% (HPLC)

Sinonimo/i:

2,5-DHBA, Acido gentisico, DHB, Hydroquinonecarboxylic acid

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About This Item

Formula condensata:
(HO)2C6H3CO2H
Numero CAS:
Peso molecolare:
154.12
Beilstein:
2209119
Numero CE:
Numero MDL:
Codice UNSPSC:
12000000
ID PubChem:
NACRES:
NA.21

Grado

matrix substance for MALDI-MS

Livello qualitativo

Saggio

>99.0% (HPLC)

Forma fisica

powder

Classi funzionali degli analiti

polymers

Classi chimiche degli analiti

glycans, lipids, organic molecules, peptides, proteins

tecniche

MALDI-MS: suitable

Punto di fusione

200-207 °C
204-208 °C (lit.)

Cationi in tracce

Ba: ≤5 mg/kg
Ca: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
K: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

ε (coefficiente d’estinzione)

>2000 at 337 nm

Stringa SMILE

OC(=O)c1cc(O)ccc1O

InChI

1S/C7H6O4/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,8-9H,(H,10,11)
WXTMDXOMEHJXQO-UHFFFAOYSA-N

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Applicazioni

2,5-Dihydroxybenzoic acid is an ionic liquid matrix used for the analysis of biomolecules using matrix-assisted laser desorption/ionization combined with mass spectrometry.
Most commonly used matrix for carbohydrates. For MALDI-MS of free neutral glycans. Produces [M+Na]+ ion; may show a weaker [M+K]+ ion. Other species may be generated by the addition of the appropriate inorganic salt.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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2,5-Dihydroxybenzoic acid butylamine and other ionic liquid matrixes for enhanced MALDI-MS analysis of biomolecules
Mank M, et al.
Analytical Chemistry, 76(10), 2938-2950 (2004)
Matrix-assisted laser desorption/ionization mass spectrometry with additives to 2,5-di-hydroxy-benzoic acid.
Karas, M., et al.,
Org. Mass Spectrom., 28, 1476-1481 (1993)
Naoki Sato
Plant & cell physiology, 56(10), 1890-1899 (2015-08-16)
Monogalactosyldiacylglycerol (MGDG) is ubiquitous in the photosynthetic membranes of cyanobacteria and chloroplasts. It is synthesized by galactosylation of diacylglycerol (DAG) in the chloroplasts, whereas it is produced by epimerization of monoglucosyldiacylglycerol (GlcDG) in at least several cyanobacteria that have been
B E Cham et al.
Clinical chemistry, 26(1), 111-114 (1980-01-01)
We have developed a specific and sensitive method for the determination of salicylic acid, salicyluric acid, and gentisic acid in urine. Any proteins present are precipitated with methyl cyanide. After centrifugation, an aliquot of the supernate is directly injected into
F Bochner et al.
Clinical pharmacology and therapeutics, 30(2), 266-275 (1981-08-01)
Single oral doses of aspirin (ASA, 1,500 mg), sodium salicylate (NaSA, 1,500 mg, 1,200 mg), and salicyluric acid (SUA, 500 mg) were given to five subjects. Serial plasma and urine samples were collected for 24 hr (plasma) and up to

Articoli

Glycosylation is known to have profound influence on various physiochemical, cellular and biological functions of proteins. Alterations in this modification are known to affect the immune system and have been associated with various pathological states such as cancer, rheumatoid arthritis, and inflammatory diseases.

Mass Spectrometry of Glycans, method comparison and products

Protocolli

Mass Spectrometry of Glycans

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