Passa al contenuto
Merck
Tutte le immagini(1)

Documenti

68957

Sigma-Aldrich

Tris(2-carbossietil)fosfina

BioUltra, suitable for electrophoresis, SDS-PAGE tested

Sinonimo/i:

TCEP

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C9H15O6P · HCl
Numero CAS:
51805-45-9
Peso molecolare:
286.65
Beilstein:
3724376
Numero MDL:
MFCD00145469
Codice UNSPSC:
12352128
ID PubChem:
329761275
NACRES:
NA.32

Nome Commerciale

BioUltra

Saggio

97.5-102.5%

Forma fisica

powder

tecniche

electrophoresis: suitable

Solubilità

H2O: soluble

Compatibilità

SDS-PAGE tested

Stringa SMILE

Cl[H].OC(=O)CCP(CCC(O)=O)CCC(O)=O

InChI

1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
PBVAJRFEEOIAGW-UHFFFAOYSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Tris(2-carboxyethyl) phosphine hydrochloride (TCEP.HCL ) is a useful reducing agent for Sulphur and nitrogen-containing compounds. TCEP.HCL and the resultant oxide are water-soluble. TCEP.HCL has electron-rich phosphorus and oxygen atoms to combine with various metals, including Rh, Ir, and Pd. It rapidly complexes with Rh and Ir in dioxane at ambient temperature. It reduces disulfide linkages in a range of peptides and proteins in biological disulfide.

Applicazioni

TCEP.HCL has been used in various bioconjugation applications, both in vitro and in vivo, to tag proteins and live organisms with great effectiveness under mild physiological circumstances. TCEP.HCL is suitable for varied biological and synthetic applications. At an acidic pH, TCEP.HCL can be used to convert organic disulfides to thiols in water irreversibly.
Reagente solubile in acqua, utilizzato per la riduzione selettiva dei disolfuri. Più stabile del DTT, viene utilizzato in applicazioni di spettrometria di massa.

Caratteristiche e vantaggi

The product has the following benefits:

  • TCEP.HCL lowers reactive oxygen species levels.
  • It increases glutathione levels and mitochondrial content.
  • It has anti-cancer effects.

Risultati analitici

agarose gel electrophorese corresponds to requirements

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H314

Classi di pericolo

Eye Dam. 1 - Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 1

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 6

1 of 6

2-Chloroacetamide ≥98.0% (HPLC)

Sigma-Aldrich

22790

2-Chloroacetamide

2-Chloroacetamide ≥98%

Sigma-Aldrich

C0267

2-Chloroacetamide

(S)-2-Aminobutane-1,4-dithiol hydrochloride 99% (titration)

Sigma-Aldrich

774405

(S)-2-Aminobutane-1,4-dithiol hydrochloride

4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester ≥98%, powder

Sigma-Aldrich

M5525

4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester

TCPP PESTANAL®, analytical standard

Supelco

32952

TCPP

THP A water-soluble, neutral, and odorless disulfide reducing agent that is more stable and effective than DTT.

Millipore

598250

THP

Siming Chen et al.
Chemical communications (Cambridge, England), 49(12), 1226-1228 (2013-01-05)
A widely used reducing agent tris-(2-carboxyethyl) phosphine significantly promotes the reaction of cisplatin with Sp1 zinc finger protein. This discovery clarifies the reactivity of cisplatin towards Sp1 zinc finger protein and implies that the reactions of platinum drugs could be
Fang-Fang Cheng et al.
The Analyst, 139(16), 3860-3865 (2014-07-01)
The expression of microRNAs (miRNAs) is related to some cancer diseases. Recently, miRNAs have emerged as new candidate diagnostic and prognostic biomarkers for detecting a wide variety of cancers. Due to low levels, short sequences and high sequence homology among
Yan Li et al.
Biosensors & bioelectronics, 67, 364-369 (2014-09-10)
The development of sensitive telomerase biosensors is hindered by the restricted accessibility of telomere strand (TS) primer and the limited enzyme reaction space, which is mainly confined by the vertical distance. In this work, we designed an electrochemical telomerase biosensor
K Zarschler et al.
Nanoscale, 6(11), 6046-6056 (2014-04-30)
For effective localization of functionalized nanoparticles at diseased tissues such as solid tumours or metastases through biorecognition, appropriate targeting vectors directed against selected tumour biomarkers are a key prerequisite. The diversity of such vector molecules ranges from proteins, including antibodies
Nicola J Blackmore et al.
The Journal of biological chemistry, 290(29), 18187-18198 (2015-06-03)
Allostery, where remote ligand binding alters protein function, is essential for the control of metabolism. Here, we have identified a highly sophisticated allosteric response that allows complex control of the pathway for aromatic amino acid biosynthesis in the pathogen Mycobacterium
Visualizza tutti i documenti correlati

Articoli

Three Methods for Critical Quality Attribute Determination of Monoclonal Antibodies

Step-by-step workflows for the intact mass analysis, peptide mapping, and N-glycan analysis of the monoclonal antibody― adalimumab, for an accurate characterization of the critical quality attributes (CQAs) to ensure drug safety and efficacy. Read more.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.