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Documenti fondamentali

22790

Sigma-Aldrich

2-Chloroacetamide

≥98.0% (HPLC)

Sinonimo/i:

Chloracetamide, alpha-Chloroacetamide

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About This Item

Formula condensata:
ClCH2CONH2
Numero CAS:
Peso molecolare:
93.51
Beilstein:
878191
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Tensione di vapore

0.05 mmHg ( 20 °C)

Saggio

≥98.0% (HPLC)

Stato

solid

Punto di fusione

116-118 °C (lit.)
118-120 °C

Solubilità

methanol: soluble 1 g/10 mL
absolute ethanol: 10 part(lit.)
water: soluble 10 parts(lit.)
diethyl ether: very slightly soluble(lit.)

Stringa SMILE

NC(=O)CCl

InChI

1S/C2H4ClNO/c3-1-2(4)5/h1H2,(H2,4,5)
VXIVSQZSERGHQP-UHFFFAOYSA-N

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Applicazioni

2-Chloroacetamide was used in the synthesis of the derivatives of 1,8-naphthyridine containing thiono groups. It was also used as a reagent for the synthesis of carboxamidomethyl esters as carboxyl protecting groups in peptide synthesis

Pittogrammi

Skull and crossbonesHealth hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Oral - Repr. 2 - Skin Sens. 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

338.0 °F

Punto d’infiammabilità (°C)

170 °C

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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J. Martinez et al.
Tetrahedron Letters, 24, 5219-5219 (1983)
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Environmental pollution (Barking, Essex : 1987), 152(1), 239-244 (2007-07-17)
Solid-phase microextraction coupled with gas chromatography-mass spectrometry (SPME-GC-MS) was used to analyze two triazine (atrazine and simazine) and three chloroacetamide herbicides (acetochlor, alachlor, and metolachlor) in water samples from a midwest US agricultural drainage ditch for two growing seasons. The
Jun Zhang et al.
Journal of agricultural and food chemistry, 59(9), 4614-4621 (2011-03-23)
A butachlor-degrading strain, designated FLY-8, was isolated from rice field soil and was identified as Paracoccus sp. Strain FLY-8 could degrade and utilize six chloroacetamide herbicides as carbon sources for growth, and the degradation rates followed the order alachlor >
Harald Møllendal et al.
The journal of physical chemistry. A, 110(6), 2139-2146 (2006-02-10)
The microwave spectrum of 2-chloroacetamide (ClCH2CONH2) has been investigated at room temperature in the 19-80 spectral range. Spectra of the 35ClCH2CONH2 and 37ClCH2CONH2 isotopomers of one conformer, which has a symmetry plane (Cs symmetry), were assigned. The amide group is
P J Britto et al.
The Journal of biological chemistry, 277(32), 29018-29027 (2002-05-23)
Of the 20 cysteines of rat brain tubulin, some react rapidly with sulfhydryl reagents, and some react slowly. The fast reacting cysteines cannot be distinguished with [14C]iodoacetamide, N-[(14)C]ethylmaleimide, or IAEDANS ([5-((((2-iodoacetyl)amino)ethyl)amino) naphthalene-1-sulfonic acid]), since modification to mole ratios 1 cysteine/dimer

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