27555

Cloxacillin sodium salt

≥95.0% (HPLC)

• Sinonimo/i: 3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt, Syntarpen sodium salt
• Formula empirica (notazione di Hill): C₁₉H₁₇ClN₃NaO₅S
• Numero CAS: 642-78-4
• Peso molecolare: 457.86
• Beilstein: 4103180
• Numero CE: 211-390-9
• Numero MDL: MFCD00063568
• Codice UNSPSC: 51102829
• ID PubChem: 57648259
• NACRES: NA.85

Proprietà

• Origine biologica: semisynthetic
• Livello qualitativo: 200
• Saggio: ≥95.0% (HPLC)
• Stato: powder or crystals
• Impurezze: ≤5% Total impurities (anhydrous)
• Colore: white to off-white
• Spettro attività antibiotica: Gram-positive bacteria
• Modalità d’azione: cell wall synthesis | interferes
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
• InChI: 1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1; SCLZRKVZRBKZCR-SLINCCQESA-M

Descrizione

Descrizione generale

Chemical structure: ß-lactam

Applicazioni

Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria.

Azioni biochim/fisiol

Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.

Altre note

Keep container tightly closed in a dry and well-ventilated place.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)