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Merck
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Documenti

14300

Sigma-Aldrich

Betaine monohydrate

≥99.0% (NT)

Sinonimo/i:

1-carboxy-n,n,n-trimethylmethanaminium hydroxide, 2-(trimethylammonio)acetate hydrate, glycine betaine hydrate

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About This Item

Formula condensata:
(CH3)3N+CH2COO- · H2O
Numero CAS:
590-47-6
Peso molecolare:
135.16
Beilstein:
3626258
Numero CE:
203-490-6
Numero MDL:
MFCD00150010
Codice UNSPSC:
51171529
ID PubChem:
57647146
NACRES:
NA.25

Saggio

≥99.0% (NT)

Forma fisica

solid

Solubilità

H2O: 0.1 g/mL, clear, colorless

Temperatura di conservazione

2-8°C

Stringa SMILE

O.C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2.H2O/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H2
NJZRLXNBGZBREL-UHFFFAOYSA-N

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Applicazioni

Betaine monohydrate:

  • is suitable for use to improve the PCR amplification of GC-rich DNA sequences by reducing the formation of secondary structure caused by GC-rich regions
  • is suitable for use as a component of PCR reaction mixture
  • is suitable for use in a study to identify yield enhancers of PCR
  • has been used to study nitrogen balance and nutrient digestibility in piglets fed diets deficient in methionine and low in compatible osmolytes
  • has also been used to compare the effects of pressure on three layered hydrates

Azioni biochim/fisiol

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Cletus Nunes et al.
Journal of pharmaceutical sciences, 93(1), 38-47 (2003-12-04)
The objectives were (1). to perform solid-state characterization of anhydrous betaine (A) and betaine monohydrate (M), (2). to develop a pressure differential scanning calorimetric (DSC) technique for the quantification of M when present as a minor component in a mixture
Meike Eklund et al.
Archives of animal nutrition, 60(4), 289-300 (2006-08-23)
A balance experiment was carried out to investigate the effects of betaine monohydrate (BET) or betaine derived from condensed molasses solubles (CMS) as a substitute for methionine and choline on nitrogen (N) balance and total tract nutrient digestibility in weaned
Theodore Spilker et al.
Journal of clinical microbiology, 50(9), 3010-3015 (2012-07-13)
The genus Achromobacter currently is comprised of seven species, including Achromobacter xylosoxidans, an opportunistic and nosocomial pathogen that displays broad-spectrum antimicrobial resistance and is recognized as causing chronic respiratory tract infection in persons with cystic fibrosis (CF). To enable strain
Russell D L Johnstone et al.
Acta crystallographica. Section B, Structural science, 65(Pt 6), 731-748 (2009-11-20)
We report the effect of pressure on the crystal structures of betaine monohydrate (BTM), L-cysteic acid monohydrate (CAM) and S-4-sulfo-L-phenylalanine monohydrate (SPM). All three structures are composed of layers of zwitterionic molecules separated by layers of water molecules. In BTM
W Henke et al.
Nucleic acids research, 25(19), 3957-3958 (1997-10-10)
Betaine improves the co-amplification of the two alternatively spliced variants of the prostate-specific membrane antigen mRNA as well as the amplification of the coding cDNA region of c-jun. It is suggested that betaine improves the amplification of these genes by
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