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61962

Sigma-Aldrich

Betaine

BioUltra, ≥99.0% (NT)

Sinonimo/i:

(Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine

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About This Item

Formula condensata:
(CH3)3N+CH2COO-
Numero CAS:
107-43-7
Peso molecolare:
117.15
Beilstein:
3537113
Numero CE:
203-490-6
Numero MDL:
MFCD00012123
Codice UNSPSC:
41116107
ID PubChem:
57651874
NACRES:
NA.25

Nome Commerciale

BioUltra

Livello qualitativo

200

Saggio

≥99.0% (NT)

Impurezze

insoluble matters, passes filter test

Solubilità

methanol: 1 M at 20 °C, clear, colorless

Anioni in tracce

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤200 mg/kg

Cationi in tracce

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

Assorbimento

≤0.05 at 280 nm in methanol at 1 M
≤0.09 at 260 nm in methanol at 1 M

Stringa SMILE

C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
KWIUHFFTVRNATP-UHFFFAOYSA-N

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Descrizione generale

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Applicazioni

Betaine has been used in reverse transcription to increase the thermal stability of proteins and to destabilize the DNA helix.

Azioni biochim/fisiol

Betaine has been shown to increase S-adenosylmethionine (SAM) levels and hence, may have a role in diminishing hepatic steatosis. It is an osmolyte which protects cells against environmental stress.
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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High plasma concentrations of homocysteine may increase risk of cardiovascular disease. Folic acid lowers plasma homocysteine by 25% maximally, because 5-methyltetrahydrofolate is a methyl donor in the remethylation of homocysteine to methionine. Betaine (trimethylglycine) is also a methyl donor in
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