01930

Adenosine 5′-monophosphate disodium salt

≥99.0% (HPLC)

• Sinonimo/i: 5′-AMPdisodium salt,, Adenylic acid disodium salt, 5′-AMP-Na₂
• Formula empirica (notazione di Hill): C₁₀H₁₂N₅Na₂O₇P
• Numero CAS: 4578-31-8
• Peso molecolare: 391.18
• Beilstein: 3586732
• Numero CE: 224-961-2
• Numero MDL: MFCD00065023
• Codice UNSPSC: 41106305
• eCl@ss: 32160414
• ID PubChem: 329747374
• NACRES: NA.51

Proprietà

• Origine biologica: microbial (Candida utilis); synthetic
• Saggio: ≥99.0% (HPLC)
• Forma fisica: powder
• Attività ottica: [α]20/D −43±2°, c = 1% in 0.5 M Na₂HPO₄ (dry matter)
• Impurezze: ≤26% water
• Stringa SMILE: [Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1; QGXLVXZRPRRCRP-IDIVVRGQSA-L

Descrizione

Applicazioni

Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). It may be used as a substrate by a variety of enzymes such as AMP-thymidine kinase (EC 2.7.1.114), AMP deaminase (EC 3.5.4.6) and 5′-nucleotidase (EC 3.1.3.5).

Adenosine 5′-monophosphate disodium salt has been used:

• as a dissolved organic phosphorus (DOP) compound to study its rate of hydrolysis in Escherichia coli lysates
• to induce calcium responses in Fura2-loaded osteoblast (C2-OB)
• as a nucleotide metabolite in the medium for the isolation, culture, and identification of glioma stem cells (GSCs)

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)