Y0001747

Exemestane

European Pharmacopoeia (EP) Reference Standard

• Sinonimo/i: 6-Methyleneandrosta-1,4-diene-3,17-dione
• Formula empirica (notazione di Hill): C₂₀H₂₄O₂
• Numero CAS: 107868-30-4
• Peso molecolare: 296.40
• Numero MDL: MFCD00866994
• Codice UNSPSC: 41116107
• ID PubChem: 329831548
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: exemestane
• Produttore/marchio commerciale: EDQM
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O
• InChI: 1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1; BFYIZQONLCFLEV-DAELLWKTSA-N
• Informazioni sul gene: human ... CYP19A1(1588)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Exemestane EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Azioni biochim/fisiol

Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H360 - H411
• Consigli di prudenza: P201 - P202 - P273 - P280 - P308 + P313 - P391
• Classi di pericolo: Aquatic Chronic 2 - Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable