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Y0000443

Flunixin meglumine

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt, Banamine

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About This Item

Formula empirica (notazione di Hill):
C14H11F3N2O2·C7H17NO5
Numero CAS:
42461-84-7
Peso molecolare:
491.46
Numero MDL:
MFCD01725419
Codice UNSPSC:
41116107
ID PubChem:
329830960
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

flunixin

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F

InChI

1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
MGCCHNLNRBULBU-WZTVWXICSA-N

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Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Flunixin meglumine (IC50 = 1 nM) can be used as a drug for animals for the management of intestinal ischaemia, colic, and endotoxemia in horses.

Azioni biochim/fisiol

COX1, COX2 and PLA2 inhibitor non-narcotic analgesic, anti-pyretic, anti-inflammatory.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Y0000445

Flunixin impurity C, European Pharmacopoeia (EP) Reference Standard

Y0000444

Flunixin impurity B, European Pharmacopoeia (EP) Reference Standard

1274607

Flunixin meglumine, United States Pharmacopeia (USP) Reference Standard

1274631

Flunixin Related Compound C, United States Pharmacopeia (USP) Reference Standard

1274630

Flunixin Related Compound B, United States Pharmacopeia (USP) Reference Standard

1274629

Flunixin Related Compound A, United States Pharmacopeia (USP) Reference Standard

PHR2305

Flunixin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2413

Flunixin Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2823

Flunixin Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

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Certificati d'analisi (COA)

Lot/Batch Number

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A J Morton et al.
Equine veterinary journal. Supplement, (39)(39), 112-116 (2011-08-04)
The effects of prostaglandins and nonsteroidal anti-inflammatory drugs (NSAIDs) on repair of equine intestinal mucosa are important since most horses with gastrointestinal diseases are routinely treated with NSAIDs, such as flunixin meglumine (FM), and these drugs can be toxic to
J F Marshall et al.
Equine veterinary journal. Supplement, (39)(39), 106-111 (2011-08-04)
Flunixin meglumine is used for treatment of equine colic despite evidence of inhibited recovery of mucosal barrier function following small intestinal ischaemic injury. This study aimed to characterise an alternative treatment (AHI-805) for abdominal pain in the horse. To determine
J Cuervo-Arango et al.
Theriogenology, 77(3), 514-524 (2011-10-01)
The development of hemorrhagic anovulatory follicles (HAF) involves luteinization and hemorrhage of the follicle. This is observed on ultrasound as an increase in the echogenicity of the granulosa layer and formation of echoic particles in the antrum. The inhibition of
Pharmacokinetic interactions of flunixin meglumine and doxycycline in broiler chickens.
F Yang et al.
Journal of veterinary pharmacology and therapeutics, 36(1), 85-88 (2012-02-02)
Pedro Paredes-Ramos et al.
Physiology & behavior, 107(1), 17-25 (2012-05-30)
Female rats display a conditioned partner preference for males that bear odors paired with different types of rewarding unconditioned stimuli (UCS). Here we examined whether tickling constitutes a rewarding UCS that supports the development of partner preferences. In Experiment 1
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