PHR1494

Pilocarpine Nitrate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: Pilocarpine nitrate salt
• Formula empirica (notazione di Hill): C₁₁H₁₆N₂O₂ · HNO₃
• Numero CAS: 148-72-1
• Peso molecolare: 271.27
• Beilstein: 4171406
• Numero CE: 205-723-7
• Numero MDL: MFCD00078497
• Codice UNSPSC: 41116107
• ID PubChem: 329823416
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to BP 503; traceable to Ph. Eur. P1700000; traceable to USP 1539009
• Famiglia di API: pilocarpine
• CdA: current certificate can be downloaded
• Confezionamento: pkg of 500 mg
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
• InChI: 1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1; PRZXEPJJHQYOGF-GNAZCLTHSA-N
• Informazioni sul gene: human ... CHRM1(1128) , CHRM3(1131)

Descrizione

Descrizione generale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pilocarpine Nitrate is a naturally occurring cholinomimetic drug, exhibiting nicotinic and muscarinic properties. It is widely used for controlling intraocular pressure in glaucoma, immediate relief of mydriasis, and to reverse mydriasis caused by cycloplegic agents.

Applicazioni

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Azioni biochim/fisiol

Nonselective muscarinic acetylcholine receptor agonist.

Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA3042 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informazioni sulla sicurezza

• Pittogrammi: GHS03,GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H272,H302,H330
• Consigli di prudenza: P210 - P220 - P260 - P264 - P301 + P312 - P304 + P340 + P310
• Classi di pericolo: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2
• Codice della classe di stoccaggio: 5.1B - Oxidizing hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable