H5501

Metile 4-idrossibenzoato

ReagentPlus^®, ≥99.0%, crystalline

• Sinonimo/i: 4-idrossibenzoato di metile, Metil estere dell’acido p-idrossibenzoico, Metilparaben
• Formula condensata: HOC₆H₄CO₂CH₃
• Numero CAS: 99-76-3
• Peso molecolare: 152.15
• Beilstein: 509801
• Numero CE: 202-785-7
• Numero MDL: MFCD00002352
• Codice UNSPSC: 51452201
• ID PubChem: 329815219
• NACRES: NA.25

Proprietà

• Livello qualitativo: 200
• Nome Commerciale: ReagentPlus^®
• Saggio: ≥99.0%
• Forma fisica: crystalline
• Punto di fusione: 125-128 °C (lit.)
• Stringa SMILE: COC(=O)c1ccc(O)cc1
• InChI: 1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3; LXCFILQKKLGQFO-UHFFFAOYSA-N

Descrizione

Applicazioni

Methyl 4-hydroxybenzoate has been used:

• in sex-linked recessive lethal (SLRL) test in Drosophila melanogaster
• as a constituent in cream formulation
• as an antifungal agent in Drosophila melanogaster culture

Azioni biochim/fisiol

Methyl 4-hydroxybenzoate, also called methyl paraben or nipagin, comprises the ester of p-hydroxybenzoic acid. It is present naturally in cloudberry, white wine and bourbon vanilla. Methyl 4-hydroxybenzoate has antimicrobial and antifungal functionality and is commercially used as a preservative in the food, cosmetic and pharmaceutical industry. Methyl 4-hydroxybenzoate has cytotoxic effects on keratinocytes in the presence of sunlight. Methyl 4-hydroxybenzoate upon solar irradiation mediates DNA damage and modulates esterase metabolism resulting in skin damage and favors cancer progression. Methyl 4-hydroxybenzoate has estrogenic functionality and upregulates estrogen-related genes.

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Informazioni sulla sicurezza

• Pittogrammi: GHS09
• Indicazioni di pericolo: H411
• Consigli di prudenza: P273 - P391 - P501
• Classi di pericolo: Aquatic Chronic 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 334.4 °F
• Punto d’infiammabilità (°C): 168 °C
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves