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2,3,5,6-Tetramethylpyrazine

analytical standard

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About This Item

Formula empirica (notazione di Hill):
C8H12N2
Numero CAS:
1124-11-4
Peso molecolare:
136.19
Beilstein:
113100
Numero CE:
214-391-2
Numero MDL:
MFCD00006146
Codice UNSPSC:
85151701
ID PubChem:
329770426
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.0% (GC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

P. eboll.

190 °C (lit.)

Punto di fusione

77-80 °C (lit.)
85-87 °C

applicazioni

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Formato

neat

Stringa SMILE

Cc1nc(C)c(C)nc1C

InChI

1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
FINHMKGKINIASC-UHFFFAOYSA-N

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Descrizione generale

2,3,5,6-Tetramethylpyrazine is a flavor compound belonging to the class of pyrazines. It is found to be a main active ingredient of the traditional Chinese medicine, Chuanxiong and Ma-Huang herbs, used to treat asthma.

Applicazioni

2,3,5,6-Tetramethylpyrazine may be used as an analytical reference standard for the quantification of the analyte in Ephedrae herba and Ephedra sinica Stapf using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H315,H319,H335

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
BCCD0128
BCBW7327
BCBR7447V
BCBM7816V
BCBH6699V

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Applications of Microbial Engineering (2013)
Separation and determination of ephedrine alkaloids and tetramethylpyrazine in ephedra sinica Stapf by gas chromatography-mass spectrometry
Journal of Chromatographic Science, 39(9), 370-374 (2001)
Analysis of tetramethylpyrazine in Ephedrae herba by gas chromatography?mass spectrometry and high-performance liquid chromatography
Lv K, et al.
Journal of Chromatography A, 878(1), 147-152 (2000)
Shouliang Wang et al.
Drug design, development and therapy, 13, 1187-1196 (2019-05-23)
Background: Bupivacaine (BUP) acts as a local anesthetic, which is extensively used for clinical patients but could generate neurotoxicity in neurons. Tetramethylpyrazine (TET) exhibits strong neuron protective effects against neurotoxicity. Hence, we investigate the effect of TET on BUP-induced neurotoxicity
Jian-Zhong Hu et al.
Journal of the neurological sciences, 324(1-2), 94-99 (2012-11-13)
In the present study, we explored the effects of tetramethylpyrazine (TMP), an alkaloid extracted from the Chinese herbal medicine Ligusticum wallichii Franchat (chuanxiong), on a rat model of contusion spinal cord injury (SCI). The contusion SCI model was induced in
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