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Merck
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Key Documents

90323

Supelco

Clofibric acid

analytical standard

Sinonimo/i:

2-(p-Chlorophenoxy)-2-methylpropionic acid, α-(p-Chlorophenoxy)isobutyric acid, Clofibric acid

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About This Item

Formula condensata:
ClC6H4OC(CH3)2CO2H
Numero CAS:
Peso molecolare:
214.65
Numero CE:
Numero MDL:
Codice UNSPSC:
77101502
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥99.0% (GC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤0.5% water

Punto di fusione

120-122 °C (lit.)

applicazioni

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

CC(C)(Oc1ccc(Cl)cc1)C(O)=O

InChI

1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)
TXCGAZHTZHNUAI-UHFFFAOYSA-N

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Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Agustina Manassero et al.
Environmental science and pollution research international, 22(2), 926-937 (2014-03-14)
A kinetic study of the photocatalytic degradation of the pharmaceutical clofibric acid is presented. Experiments were carried out under UV radiation employing titanium dioxide in water suspension. The main reaction intermediates were identified and quantified. Intrinsic expressions to represent the
Da-Bing Ren et al.
Journal of chromatography. A, 1355, 80-85 (2014-06-22)
Selection of an appropriate solvent system is of great importance for a successful counter-current chromatography separation. In this work, the nonrandom two-liquid (NRTL) model, a thermodynamic method, was used for predicting the partition coefficient based on a few measured partition
Zein Shaban Ibrahim et al.
Bioscience, biotechnology, and biochemistry, 78(9), 1550-1559 (2014-07-24)
Peroxisome proliferator activated receptor α (PPARα) ligands, fibrates used to control hyperlipidemia. We demonstrated CYP2B induction by clofibric acid (CFA) however, the mechanism was not clear. In this study, HepG2 cells transfected with expression plasmid of mouse constitutive androstane receptor
Martin J A Schackmann et al.
Biochimica et biophysica acta, 1851(2), 231-237 (2014-12-17)
X-linked adrenoleukodystrophy (X-ALD) is a neurometabolic disease that is caused by mutations in the ABCD1 gene. ABCD1 protein deficiency impairs peroxisomal very long-chain fatty acid (VLCFA) degradation resulting in increased cytosolic VLCFA-CoA levels, which are further elongated by the VLCFA-specific
Julia Martín et al.
The Science of the total environment, 503-504, 97-104 (2014-06-10)
Sewage sludge disposal onto lands has been stabilized previously but still many pollutants are not efficiently removed. Special interest has been focused on pharmaceutical compounds due to their potential ecotoxicological effects. Nowadays, there is scarce information about their occurrence in

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