410225

Glicina

≥98.5%, ACS reagent for peptide synthesis

• Sinonimo/i: Acido aminoacetico, Acido aminoetanoico, Glicocolla
• Formula condensata: NH₂CH₂COOH
• Numero CAS: 56-40-6
• Peso molecolare: 75.07
• Beilstein: 635782
• Numero CE: 200-272-2
• Numero MDL: MFCD00008131
• Codice UNSPSC: 12352209
• eCl@ss: 32160406
• ID PubChem: 24865701
• NACRES: NA.21

Proprietà

• product name: Glicina, ACS reagent, ≥98.5%
• Grado: ACS reagent
• Livello qualitativo: 200
• Saggio: ≥98.5%
• Forma fisica: powder, crystals or granules
• Impurezze: H₂SO₄, passes test (darkened); Hydrolyzable subsances, passes test
• Residuo alla calcinazione: ≤0.1%
• Colore: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• Punto di fusione: 240 °C (dec.) (lit.)
• Anioni in tracce: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• Cationi in tracce: NH₄⁺: ≤0.005%; heavy metals: ≤0.002% (by ICP)
• applicazioni: peptide synthesis
• Stringa SMILE: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5); DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Informazioni sul gene: rat ... Grin2a(24409)

Descrizione

Descrizione generale

Glycine is the simplest amino acid building block.

Applicazioni

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Azioni biochim/fisiol

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Neurotrasmettitore inibitore nella colonna vertebrale, regolatore allosterico di recettori NMDA.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)