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Key Documents

36127

Supelco

Climbazole

PESTANAL®, analytical standard

Sinonimo/i:

1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one

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About This Item

Formula empirica (notazione di Hill):
C15H17ClN2O2
Numero CAS:
Peso molecolare:
292.76
Beilstein:
618020
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Nome Commerciale

PESTANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
NMR: suitable
gas chromatography (GC): suitable

Punto di fusione

96-100 °C

Compatibilità

passes test for identity (NMR)

applicazioni

agriculture
environmental

Formato

neat

Stringa SMILE

CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n2ccnc2

InChI

1S/C15H17ClN2O2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14H,1-3H3
OWEGWHBOCFMBLP-UHFFFAOYSA-N

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Descrizione generale

Climbazole is an imidazole antifungal agent, which is widely used as an active ingredient in anti-dandruff (AD) shampoos since, it inhibits the microbial growth and improves skin barrier on scalp.

Applicazioni

Climbazole may be used as a reference standard in the determination of climbazole in environmental samples and in samples of anti-dandruff shampoo using ultra-high-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Note legali

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

Exclamation markEnvironment

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Certificati d'analisi (COA)

Lot/Batch Number

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I clienti hanno visto anche

Alex A Pérez-Rivera et al.
Mutation research, 672(1), 27-39 (2008-10-28)
Climbazole is an imidazole antifungal agent that can provide anti-dandruff benefits when incorporated into a shampoo matrix. A series of genotoxicity studies were performed to support the human safety of this azole antifungal drug. Climbazole was not mutagenic in the
W Wigger-Alberti et al.
Praxis, 90(33), 1346-1349 (2001-09-06)
Pityrosporum ovale appears to play an important role in the pathogenesis of dandruff as a symptom of seborrheic dermatitis. Climbazole is an antimycotic agent with a high in vitro and in vivo efficacy against P. ovale. In the presented work
A Schmidt
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 44(4), 193-197 (1997-06-01)
Malassezia pachydermatis is a yeast-like, mainly zoophilic fungus, also known as Malassezia canis. It can be isolated in 20-50% from normal ear cerumen specimen from dogs or cats and has an even higher prevalence in non-suppurative otitis externa in animal
Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatography--tandem mass spectrometry
Chen F-Z, et al.
Analytical and Bioanalytical Chemistry, 404(10), 3175-3188 (2012)
Ultra-high-performance liquid chromatography?tandem mass spectrometry measurement of climbazole deposition from hair care products onto artificial skin and human scalp.
Chen G, et al.
Journal of Chromatography A, 1317, 155-158 (2013)

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