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32002

Sigma-Aldrich

Sodium 5,5-diethylbarbiturate

purum, ≥99.0% (NT)

Sinonimo/i:

5,5-Diethylbarbituric acid sodium salt, Barbitone, Sodium barbital, Veronal sodium salt

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About This Item

Formula empirica (notazione di Hill):
C8H11N2NaO3
Numero CAS:
Peso molecolare:
206.17
Beilstein:
3921202
Numero CE:
Numero MDL:
Codice UNSPSC:
12161703
ID PubChem:
NACRES:
NA.77

Grado

purum

Livello qualitativo

Saggio

≥99.0% (NT)

Forma fisica

powder or crystals

Controllo stupefacenti

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

Condizioni di stoccaggio

(Tightly closed. Dry.)

tecniche

GC/MS: suitable
HPLC: suitable
activity assay: suitable

Colore

colorless

pH

9.0-10.5

Punto di fusione

>287.1 °C (> 548.8 °F)

Solubilità

water: soluble 103.1 g/L at 20 °C (68 °F)

Densità

1.418 g/cm3 at 20 °C ( 68 °F)

Compatibilità

suitable for microbiology
suitable for molecular biology

applicazioni

cell analysis

Stringa SMILE

[Na+].CCC1(CC)C(=O)NC([O-])=NC1=O

InChI

1S/C8H12N2O3.Na/c1-3-8(4-2)5(11)9-7(13)10-6(8)12;/h3-4H2,1-2H3,(H2,9,10,11,12,13);/q;+1/p-1
RGHFKWPGWBFQLN-UHFFFAOYSA-M

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Descrizione generale

Sodium 5,5-diethyl barbiturate, also known as Barbital sodium, is a long-acting barbiturate that can significantly depress various metabolic processes at high doses. This weak acid has widespread applications in scientific fields, particularly as a buffering solution in biochemical and biological experiments due to its buffering capabilities. It is particularly well-suited for scenarios requiring lower buffer capacity without compromising pH stability. This buffering effect is achieved through the equilibrium between the acid and its corresponding anion, effectively stabilizing the pH within the desired range. Additionally, Sodium 5,5-diethyl barbiturate has potential applications in histology, and biochemical research, including uses in enzyme assays, cell structure staining, and electrophoresis.

Applicazioni

Sodium 5,5-diethyl barbiturate has been used as a component of Michaeli′s buffer, a commonly used buffer solution that helps maintain ideal conditions for histological and histopathological analyses. It is also utilized as a biological buffer in immunoelectrophoresis, hemolytic assays and fixative solutions.

Azioni biochim/fisiol

Sedative/hypnotic

Caratteristiche e vantaggi

  • Suitable for electrophoresis and enzymatic assays
  • High purity product for research applications
  • Component of Michaeli′s buffer

Attenzione

Substance of abuse. Regulatory approval may be required for purchase. Comply with applicable laws. Exercise responsible use.

Altre note

For additional information on our range of Biochemicals, please complete this form.
This product is intended for research purposes only, and it is not meant for human consumption.
Sales restrictions may apply

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Pittogrammi

Health hazardExclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

Organi bersaglio

Nervous system, Respiratory system

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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The Journal of clinical investigation, 96(3), 1564-1572 (1995-09-01)
Complement activation contributes to the systemic inflammatory response induced by cardiopulmonary bypass. At the cellular level, cardiopulmonary bypass activates leukocytes and platelets; however the contribution of early (3a) versus late (C5a, soluble C5b-9) complement components to this activation is unclear.
Y Hiasa et al.
Carcinogenesis, 3(10), 1187-1190 (1982-01-01)
Phenobarbital (PB) and barbital (BB) promoted the development of thyroid tumors in rats treated with a sub-effective dose of N-bis(2-hydroxypropyl)nitrosamine (DHPN) for thyroid tumorigenesis. Rats were given s.c. injections of 70 mg DHPN/100 g body weight once a week for

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