PGI-RO

Phosphoglucose Isomerase (PGI)

from yeast

• Sinonimo/i: glucose-6-phosphate isomerase
• Classificazione EC (Enzyme Commission): 5.3.1.9 (BRENDA, IUBMB)
• Codice UNSPSC: 12352204

Proprietà

• Origine biologica: yeast
• Livello qualitativo: 100
• Stato: suspension
• Attività specifica: ~350 units/mg protein (at 25 °C with fructose-6-P as the substrate.)
• Confezionamento: pkg of 1 mL (10127396001 [2 mg]); pkg of 1 mL (10128139001 [10 mg])
• Produttore/marchio commerciale: Roche
• pH ottimale: 7.0-7.6
• Temperatura di conservazione: 2-8°C

Descrizione

Descrizione generale

Phosphoglucose Isomerase is an enzyme which possesses diagnostic potential when fractionated by cellulose acetate electrophoresis. This cytosolic enzyme plays an important role during glycolysis and glucogenesis. It acts as an tumor-secreted cytokine and autocrine motility factor. It is used as neurotrophic factor, maturation factor and as serine proteinase inhibitor.

Specificità

Phosphoglucose isomerase (PGI) is specific for G6P (K_m = 0.7 mM) and fructose-6-phosphate (F6P).

Applicazioni

Isomerization of ketoses to aldoses.

Qualità

Contaminants: <0.01% F6P-K, GR, 6-PGDH and PGluM, each, <0.2% β-fructosidase

Stato fisico

Suspension in 3.2 M ammonium sulfate solution, pH approximately 6

Nota sulla preparazione

Storage conditions (working solution): A solution of PGI in 20 mM Tris, pH 8.1, containing 0.2 mg BSA/ml, is stable approx. 1 week at 2 to 8 °C.

Altre note

For life science research only. Not for use in diagnostic procedures.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): No data available
• Punto d’infiammabilità (°C): No data available