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Key Documents

MAB8783

Sigma-Aldrich

Anti-SARS Antibody, S Specific, clone 154C

clone 154C, Chemicon®, from mouse

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

154C, monoclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Chemicon®

tecniche

ELISA: suitable
immunofluorescence: suitable
neutralization: suitable
western blot: suitable

Condizioni di spedizione

wet ice

Descrizione generale

Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus, called SARS-associated coronavirus (SARS-CoV). Human coronaviruses (HCoVs) were previously only associated with mild diseases. The SARS-CoV genome contains five major open reading frames (ORFs) that encode the replicase polyprotein; the spike (S), envelope (E), and membrane (M) glycoproteins; and the nucleocapsid protein (N). It is an enveloped, positive-sense, single-stranded RNA virus.

Specificità

SARS-associated coronavirus (SARS-CoV) S proteins.

Immunogeno

Epitope: S Specific

Applicazioni

Anti-SARS Antibody, S Specific, clone 154C is suitable for the detection of SARS in:
  • Immunofluorescence
  • ELISA
  • Western Blot
  • Immunoblot
  • Neutralization

Optimal dilutions must be determined by the end user.

Research Category
Infectious Diseases

Research Sub Category
Infectious Diseases - Viral

Azioni biochim/fisiol

Severe acute respiratory syndrome (SARS) -associated coronavirus′ (SARS-CoV) spike glycoprotein mediates the viral entry by binding to the host cell receptor. SARS spike protein is the target for vaccine development and antibody therapies.

Stato fisico

Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB, 0.25M sodium chloride with 0.1% sodium azide as a preservative

Stoccaggio e stabilità

Store at 2 to 8°C for up to 12 months from date of receipt.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Visita l’Archivio dei documenti

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses.
Letko M, et al.
Nature microbiology, 5(4), 562-569 (2020)
An imperative need for research on the role of environmental factors in transmission of novel coronavirus (COVID-19).
Qu G, et al.
Environmental Science & Technology, 57(7), 3730-3732 (2020)
An Imperative Need for Research on the Role of Environmental Factors in Transmission of Novel Coronavirus (COVID-19).
Guangbo Qu et al.
Environmental science & technology, 54(7), 3730-3732 (2020-03-24)
The Nucleocapsid Protein of SARS-CoV-2: a Target for Vaccine Development.
Noton K Dutta et al.
Journal of virology, 94(13) (2020-06-18)

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