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Key Documents

MAB16983Z

Sigma-Aldrich

Anti-Integrin α4 Antibody, clone P1H4, azide free

clone P1H4, Chemicon®, from mouse

Sinonimo/i:

CD49d, MAB16983

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

P1H4, monoclonal

Reattività contro le specie

human, primate

Produttore/marchio commerciale

Chemicon®

tecniche

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotipo

IgG1

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... ITGA4(3676)

Specificità

The involvement of integrins in vascular proliferation, adhesion, and wound repair and have been well-documented. The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits Monoclonal antibody MAB16983Z was produced by immunization with human T lymphocytes. The antibody is reactive with integrin alpha-4 from primate and human species.

Applicazioni

Anti-Integrin α4 Antibody, clone P1H4, azide free is an antibody against Integrin α4 for use in ELISA, FC, IC, IH & IP.
Immunohistochemistry (preferred fixatives are acetone and alcohols)

Immunocytochemistry

Immunoprecipitation

FACS Analysis

ELISA

Radioimmunoassay

Biological Activity: MAB16983Z inhibits CS-1 and VCAM binding.

Optimal working dilutions must be determined by end user.

Stato fisico

Format: Purified
Protein A Purified immunoglobulin in 0.01M PBS pH 7.1, 0.15M NaCl containing no preservatives.

Risultati analitici

Control
Widely expressed, Intestinal mucosa

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Arti V Shinde et al.
Matrix biology : journal of the International Society for Matrix Biology, 41, 26-35 (2014-11-30)
Prompt deposition of fibronectin-rich extracellular matrix is a critical feature of normal development and the host-response to injury. Fibronectin isoforms that include the EDA and EDB domains are prominent in these fibronectin matrices. We now report using human dermal fibroblast
Neisseria gonorrhoeae-induced transactivation of EGFR enhances gonococcal invasion.
Swanson KV, Griffiss JM, Edwards VL, Stein DC, Song W.
Cellular Microbiology null
N Assa-Munt et al.
Biochemistry, 40(8), 2373-2378 (2001-05-01)
The Arg-Gly-Asp (RGD) sequence serves as the primary integrin recognition site in extracellular matrix proteins, and peptides containing this sequence can mimic the activities of the matrix proteins. Depending on the context of the RGD sequence, an RGD-containing peptide may
Neisseria meningitidis adhesin NadA targets beta1 integrins: functional similarity to Yersinia invasin.
Nagele, V; Heesemann, J; Schielke, S; Jimenez-Soto, LF; Kurzai, O; Ackermann, N
The Journal of Biological Chemistry null

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