FCMAB404PE

Milli-Mark^® Anti-Tie2/TEK-PE Antibody, clone Ab33

clone Ab33, Milli-Mark^®, from mouse

• Sinonimo/i: Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, hTIE2, p140 TEK, CD202b
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Coniugato: PE
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: Ab33, monoclonal
• Reattività contro le specie: human
• Produttore/marchio commerciale: Milli-Mark^®
• tecniche: flow cytometry: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_000450
• N° accesso UniProt: Q02763
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... TEK(7010)

Descrizione

Descrizione generale

TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin-like loops separated by three epidermal growth factor-like repeats that are connected to three fibronectin type III-like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.

Specificità

Antibody recognizes Human Tie2/TEK.

Immunogeno

Fusion protein corresponding to residues 1-745 of human Tie2/TEK with a C-terminal His6-tag purified from infected SF-9 cells.

Applicazioni

Milli-Mark Anti-Tie2/TEK-PE Antibody, clone Ab33 is an antibody against Tie2/TEK for use in FC.

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

Qualità

Evaluated by flow cytometry using HUVEC cells.

Descrizione del bersaglio

126 kDa Calculated

Stato fisico

Protein G Purified

Purified mouse monoclonal IgG1k conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Stoccaggio e stabilità

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Risultati analitici

Control
HUVEC cells

Note legali

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable