1.15092

EXtrelut^® NT

packing material for the production of large extraction columns

• Numero CAS: 68855-54-9
• Numero MDL: MFCD00132803
• Codice UNSPSC: 41115711
• Numero indice EU: 272-489-0

Proprietà

• Livello qualitativo: 100
• tecniche: supported liquid extraction (SLE): suitable
• pH: 10 (20 °C, 100 g/L in H₂O)
• Punto di fusione: >450 °C
• Solubilità: 0.0037 g/L
• Densità: 2.36 g/cm³ at 20 °C
• Densità bulk: 300 kg/m³
• Temperatura di conservazione: 15-25°C
• InChI: 1S/C4H9.Li/c1-3-4-2;/h1,3-4H2,2H3;; MZRVEZGGRBJDDB-UHFFFAOYSA-N

Descrizione

Descrizione generale

Extrelut^® NT semplifica l′estrazione liquido-liquido nella sua forma più efficace utilizzando una fase solida a base di terra diatomacea di elevata purezza con fori ampi chimicamente inerte. Sono disponibili tre tipi di colonne in base al volume del campione: Extrelut NT1 può accogliere un massimo di 1 ml, Extrelut NT3 può accogliere 3 ml ed Extrelut NT20 può accogliere fino a 20 ml di campione.

Applicazioni

• Heart failure biomarkers BNP and NT-proBNP detection using optical labels.: This research utilizes EXtrelut NT for the extraction and analysis of heart failure biomarkers BNP and NT-proBNP. The study highlights the role of EXtrelut NT in enhancing the sensitivity and accuracy of biomarker detection using optical labels, which is critical for the early diagnosis and monitoring of heart failure (Goryacheva et al., 2022).


• Evaluation of the Analytical Performance of BNP and NT-proBNP Assays on the Atellica CI 1900 Analyzer.: This study employs EXtrelut NT to streamline the extraction of BNP and NT-proBNP biomarkers from human plasma and serum samples. The research demonstrates the efficacy of EXtrelut NT in ensuring precise and reproducible results in high-throughput analytical workflows, validating the performance of the Atellica CI 1900 Analyzer in clinical diagnostics (Rhea-McManus et al., 2023).


• NT-proBNP detection with a one-step magnetic lateral flow channel assay.: This study uses EXtrelut NT to facilitate the extraction and purification of NT-proBNP from whole blood samples. The research highlights the role of EXtrelut NT in achieving high sensitivity and accuracy in NT-proBNP detection using a novel magnetic lateral flow assay, which is crucial for point-of-care diagnostics of heart failure (Strohmaier-Nguyen et al., 2024).


• Sample-to-answer lateral flow assay with integrated plasma separation and NT-proBNP detection.: This research employs EXtrelut NT in the development of a sample-to-answer lateral flow assay for NT-proBNP detection. The study emphasizes the pack′s role in ensuring efficient plasma separation and high-sensitivity detection of NT-proBNP in clinical blood samples, highlighting its application in point-of-care testing (Strohmaier-Nguyen et al., 2024).

Risultati analitici

Aspetto: polvere granulare con buone proprietà reologiche (free flowing)
Densità bulk: 18,0 - 36,0 g/100 mL
Alcalinità (colonna Extrelut-20): <0,25mmol
Purezza
- assorbanza 280 nm:
≤ 0,109
- assorbanza 250 nm: ≤ 0,157
- assorbanza 230 nm: ≤ 0,300
- GC: picchi di contaminazione assenti o insignificanti

Note legali

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H372
• Consigli di prudenza: P260 - P264 - P270 - P314 - P501
• Classi di pericolo: STOT RE 1 Inhalation
• Organi bersaglio: Lungs
• Codice della classe di stoccaggio: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable