1.02975

D-sorbitolo

FP, liquid, (sorbitol syrup, noncrystallizing), EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF, E 420

• Sinonimo/i: D-glucitolo
• Formula empirica (notazione di Hill): C₆H₁₄O₆
• Numero CAS: 50-70-4
• Peso molecolare: 182.17
• Beilstein: 1721899
• Numero MDL: MFCD00004708
• Codice UNSPSC: 12352104
• Numero E: E420

Proprietà

• agenzia: BP; NF; Ph. Eur.
• Livello qualitativo: 500
• Densità del vapore: <1 (vs air)
• Tensione di vapore: <0.1 mmHg ( 25 °C)
• Nome Commerciale: EMPROVE^® ESSENTIAL
• Stato: liquid; viscous liquid
• pH: 6 (20 °C in H₂O, 50% solution)
• Punto di fusione: 98-100 °C (lit.)
• Densità: 1.3 g/cm³ at 20 °C
• applicazioni: liquid formulation; pharmaceutical
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1; FBPFZTCFMRRESA-JGWLITMVSA-N

Descrizione

Descrizione generale

Whether suspensions, emulsions or solutions – oral liquid dosage forms offer a number of advantages: They allow for individual dosing, are easy to swallow and are suitable for pediatric or geriatric applications. On the other hand, formulators face considerable challenges concerning solubility, API stability in aqueous systems, or taste that can often make a decisive difference. Our large product portfolio covers all excipients required for oral liquid formulation, as solvents and surfactants, flavors, ph adjustments and buffers, preservatives and viscosity enhancers.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Applicazioni

Sorbitol is a sugar alcohol which is frequently used as sweetener in oral liquid pharmaceutical formulations, as well as bulking agent, sugar substitute or humectant in cosmetics and food and beverage. Non-crystallizing sorbitol is especially used as humectant and plasticizer for soft-gel capsules.

Note legali

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1