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840635P

Avanti

12:0 PA

1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt), powder

Sinonimo/i:

1,2-didodecanoyl-sn-glycero-3-phosphate (sodium salt); DLPA; PA(12:0/12:0)

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About This Item

Formula empirica (notazione di Hill):
C27H52O8PNa
Numero CAS:
108321-06-8
Peso molecolare:
558.66
Numero MDL:
MFCD00151761
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (TLC)

Stato

powder

Confezionamento

pkg of 1 × 200 mg (840635P-200mg)
pkg of 1 × 25 mg (840635P-25mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 840635P

Tipo di lipide

phospholipids
cardiolipins

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]

InChI

1S/C27H53O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-26(28)33-23-25(24-34-36(30,31)32)35-27(29)22-20-18-16-14-12-10-8-6-4-2;/h25H,3-24H2,1-2H3,(H2,30,31,32);/q;+1/p-1/t25-;/m1./s1
CIOHBYXGWWPOIS-VQIWEWKSSA-M

Descrizione generale

12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate) is a sodium salt of modified lipid, wherein C-1, C-2 of glycerol is substituted with didodecanoyl and C-3 of glycerol is substituted with phosphatidic acid group.

Applicazioni

12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt)) has been used as an internal lipid standard in the matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis. It may be used as a lipid standard:
  • for the quantification of phospholipids by high-performance liquid chromatography coupled to tandem mass spectrometryelectrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
  • for the quantification of lipids in cold-pressed rapeseed oils based on direct infusion electrospray ionization tandem mass spectrometry
  • in liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis

Azioni biochim/fisiol

Phosphatidic acid (PA) might serve as a modulator of phagocyte respiratory burst.

Confezionamento

5 mL Amber Glass Screw Cap Vial (840635P-200mg)
5 mL Amber Glass Screw Cap Vial (840635P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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Marie Garnier-Lhomme et al.
PloS one, 4(1), e4255-e4255 (2009-01-24)
The cytoplasm of eukaryotic cells is a highly dynamic compartment where membranes readily undergo fission and fusion to reorganize the cytoplasmic architecture, and to import, export and transport various cargos within the cell. The double membrane of the nuclear envelope
Ya Xie et al.
Food chemistry, 285, 194-203 (2019-02-25)
Microwave pretreatment of rapeseeds prior to cold-pressing is a simple and desirable method for producing high quality oils. In this study, a rapid and sensitive lipid profiling platform employing an accurate quantification strategy was established based on direct infusion electrospray
Yuchen Sun et al.
Metabolites, 9(11) (2019-11-07)
Extracellular vesicles (EVs) consist of lipid bilayers, occur in various biofluids, and are invaluable in biomarker screening. Liquid chromatography coupled with high-resolution mass spectrometry (LC-MS) was recently used to study comprehensive EV lipid profiles in vitro. The aim of this
Emily R Schenk et al.
Journal of mass spectrometry : JMS, 50(1), 88-94 (2015-01-21)
Bacterial resistance to antibiotics has become an increasing threat, requiring not only the development of new targets in drug discovery, but more importantly, a better understanding of cellular response. In the current study, three closely related Escherichia coli strains, a
Yasunori Watanabe et al.
Nature communications, 6, 7922-7922 (2015-08-04)
Eukaryotic cells are compartmentalized into membrane-bounded organelles whose functions rely on lipid trafficking to achieve membrane-specific compositions of lipids. Here we focused on the Ups1-Mdm35 system, which mediates phosphatidic acid (PA) transfer between the outer and inner mitochondrial membranes, and

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