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840044C

Avanti

Soy PI

Avanti Research - A Croda Brand 840044C

Sinonimo/i:

L-α-phosphatidylinositol (Soy) (sodium salt)

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About This Item

Numero CAS:
Codice UNSPSC:
12352211
NACRES:
NA.25

Saggio

>99% (TLC)

Stato

liquid

Confezionamento

pkg of 1 × 1 mL (840044C-10mg)
pkg of 1 × 2 mL (840044C-50mg)
pkg of 1 × 2.5 mL (840044C-25mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand 840044C

Concentrazione

10 mg/mL (840044C-10mg)
10 mg/mL (840044C-25mg)
25 mg/mL (840044C-50mg)

Tipo di lipide

phosphoglycerides

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP([O-])(OC[C@@]([H])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[Na+]

InChI

1S/C43H79O13P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(45)55-35(34-54-57(51,52)56-43-41(49)39(47)38(46)40(48)42(43)50)33-53-36(44)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35,38-43,46-50H,3-10,12,14-16,19-34H2,1-2H3,(H,51,52);/q;+1/p-1/b13-11-,18-17-;/t35-,38?,39-,40?,41?,42?,43-;/m1./s1
DCDQYHYLAGWAPO-UQZYTPKFSA-M

Descrizione generale

L-α-phosphatidylinositol (Soy) is a naturally occurring, negatively charged glycerophospholipid with an inositol ring. It is found in biological membranes, which are involved in scaffolding, cellular compartmentalization and signal transduction.

Applicazioni

Soy PI has been used in PI 3-kinase assay.

Azioni biochim/fisiol

L-α-phosphatidylinositol (Soy) acts as a cellular mediator in signal transduction processes. It is used to design therapeutic delivery vehicles for drug delivery. Soy PI also contributes to the regulation of cholesterol metabolism.

Confezionamento

5 mL Clear Glass Sealed Ampule (840044C-10mg)
5 mL Clear Glass Sealed Ampule (840044C-25mg)
5 mL Clear Glass Sealed Ampule (840044C-50mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pittogrammi

Skull and crossbonesHealth hazard

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

does not flash

Punto d’infiammabilità (°C)

does not flash


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Liposomes consisted of phosphatidylinositol (PI) and phosphatidylcholine (PC) have been utilized as delivery vehicle for drugs and proteins. In the present work, we studied the effect of soy PI on physical properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes such as phase state
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
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The Journal of biological chemistry, 294(50), 19081-19098 (2019-11-07)
Phosphatidylinositol-transfer proteins (PITPs) are key regulators of lipid signaling in eukaryotic cells. These proteins both potentiate the activities of phosphatidylinositol (PtdIns) 4-OH kinases and help channel production of specific pools of phosphatidylinositol 4-phosphate (PtdIns(4)P) dedicated to specific biological outcomes. In
Phospholipids as cardiovascular therapeutics
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Current Opinion in Investigational Drugs, 9(3), 281-285 (2008)

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