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Key Documents

791640C

Avanti

15:0-18:1-d7-PG

Avanti Research - A Croda Brand 791640C

Sinonimo/i:

1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] (sodium salt)

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About This Item

Formula empirica (notazione di Hill):
C39H67D7NaO10 P
Numero CAS:
Peso molecolare:
764.01
Codice UNSPSC:
41141825
NACRES:
NA.25

Saggio

>99% (TLC)

Forma fisica

liquid

Confezionamento

pkg of 1 × 1 mL (791640C-1mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand 791640C

Concentrazione

1 mg/mL (791640C-1mg)

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Categorie correlate

Descrizione generale

15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] is a deuterated phospholipid. The lipid comprises phosphatidylglycerol attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylglycerol is anionic phospholipid and is associated with thylakoids, microsomal and mitochondrial membrane.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH LIPIDOMIX Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Applicazioni

15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] (sodium salt),) has been used:
  • as a component of extraction solvent for lipid isolation from biological samples
  • as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis
  • as an isotopically labeled lipid internal standard for correction of lipids detected in lipid droplets using shotgun mass spectrometry analysis

Azioni biochim/fisiol

Phosphatidylglycerol (PG) plays a key role in photosynthesis. Cardiolipin is synthesized from PG. PG mediates many mitochondrial functions.

Confezionamento

2 mL Amber Glass Sealed Ampule (791640C-1mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

Pittogrammi

Skull and crossbonesHealth hazard

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

does not flash

Punto d’infiammabilità (°C)

does not flash


Certificati d'analisi (COA)

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Shin-Ya Morita et al.
Scientific reports, 5, 11737-11737 (2015-07-01)
Phosphatidylglycerol (PG) and cardiolipin (CL) are synthesized in mitochondria and regulate numerous biological functions. In this study, a novel fluorometric method was developed for measuring PG and CL using combinations of specific enzymes and Amplex Red. This assay quantified the
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using

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