P38706
Phthalazine
98%
Sinonimo/i:
β-Phenodiazine, 2,3-Benzodiazine, 2,3-Diazanaphthalene, Benzo[d]pyridazine
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About This Item
Formula empirica (notazione di Hill):
C8H6N2
Numero CAS:
Peso molecolare:
130.15
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Saggio
98%
Forma fisica
crystals
P. eboll.
189 °C/29 mmHg (lit.)
Punto di fusione
89-92 °C (lit.)
Temperatura di conservazione
2-8°C
Stringa SMILE
c1ccc2cnncc2c1
InChI
1S/C8H6N2/c1-2-4-8-6-10-9-5-7(8)3-1/h1-6H
LFSXCDWNBUNEEM-UHFFFAOYSA-N
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Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Aquatic Chronic 3 - Muta. 2
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I clienti hanno visto anche
Mehdi Rashidi et al.
Inorganic chemistry, 49(18), 8435-8443 (2010-08-18)
The reaction of phthalazine with the binuclear organoplatinum complexes [Me(2)Pt(μ-SMe(2))(μ-dppm)PtR(2)], R = Me, Ph, 4-tolyl or R(2) = (CH(2))(4), dppm = bis(diphenylphosphino)methane, gives the corresponding complexes [Me(2)Pt(μ-phthalazine)(μ-dppm)PtR(2)] by displacement of the bridging dimethylsulfide ligand. The structures of [Me(2)Pt(μ-SMe(2))(μ-dppm)PtMe(2)] and [Me(2)Pt(μ-phthalazine)(μ-dppm)PtMe(2)]
Manuel Sánchez-Moreno et al.
The Journal of antimicrobial chemotherapy, 67(2), 387-397 (2011-12-01)
To evaluate the in vitro leishmanicidal activity of imidazole-based (1-4) and pyrazole-based (5-6) benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis. The in vitro activity of compounds 1-6 was assayed on extracellular promastigote and axenic amastigote forms, and on intracellular
Design and synthesis of selective and potent orally active S1P5 agonists.
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ChemMedChem, 5(10), 1693-1696 (2010-09-04)
Fadi M Awadallah et al.
European journal of medicinal chemistry, 52, 14-21 (2012-03-24)
New phthalazine-based vasodilators were synthesized through the chloroacylation of the starting compound 1-hydrazinophthalazine 4 to give the two key intermediates 5 and 7. These intermediates were used to alkylate various cyclic amines to furnish the final compounds 6a-h and 8a-h.
Michał Achmatowicz et al.
The Journal of organic chemistry, 74(2), 795-809 (2008-12-18)
p38 MAP kinase inhibitors have attracted considerable interest as potential agents for the treatment of inflammatory diseases. Herein, we describe a concise and efficient synthesis of inhibitor 1 that is based on a phthalazine scaffold. Highlights of our approach include
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